Atopic Dermatitis: Drug Delivery (Management) and Approaches (Strategies) in Perspective

Virendra N. Sehgal

doi:10.1055/s-0040-1712790

Annals of the National Academy of Medical Sciences (India), Inhaltsverzeichnis

CC BY-NC-ND 4.0 · Ann Natl Acad Med Sci 2018; 54(02): 078-089
DOI: 10.1055/s-0040-1712790

Review Article

Atopic Dermatitis: Drug Delivery (Management) and Approaches (Strategies) in Perspective

Virendra N. Sehgal

Dermato-Venereology (Skin/VD) Center, Sehgal Nursing Home, Panchwati, Delhi.

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Abstract

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ABSTRACT

Age-related cutaneous manifestations are deﬁnitive pointer to the diagnosis of atopic dermatitis, the conﬁrmation of which is solicited by 3 major and 3 minor criteria. Its unpredictable course is punctuated by exacerbations and remissions. Several treatment options, namely: 1^st, 2^nd and 3^rd line are in vogue ever since. The 1^st line envisages general measures, 2^nd encompasses topical applications, while the 3^rd take into account drug therapy comprising, systemic Corticosteroids, Cyclosporin, Azathioprine, Thymopentin, Interferon–therapy, Topical Calcineurin inhibitors: Tacrolimus and Pimecrolimus. The mode of action, their dosages and adverse drug reaction (ADR), in particular, have been focused in this paper with special attention to refresh their drug delivery (management) approaches (strategies) in perspective. An endeavor to focus attention to emerging etio-pathogenesis, and its application in the contemporary context has also been made.

Keywords:

Atopic dermatitis - Immunoglobulins E - Cyclosporin - Azathioprine - Thymopentin - Interferon-therapy

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Referenzen

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