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CC BY-NC-ND 4.0 · Rev Bras Ortop (Sao Paulo) 2021; 56(04): 419-424
DOI: 10.1055/s-0040-1712136
Artigo de Atualização
Oncologia

Sarcomas de partes moles nos membros, mais comuns e tão graves quanto os sarcomas ósseos[∗]

Artikel in mehreren Sprachen: português | English
Karen Voltan 
1   Departamento de Ortopedia e Traumatologia, Faculdade de Ciências Médicas da Universidade Estadual de Campinas, Campinas, SP, Brasil
,
André Mathias Baptista 
2   Instituto de Ortopedia e Traumatologia, Hospital das Clinicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brasil
,
Maurício Etchebehere 
1   Departamento de Ortopedia e Traumatologia, Faculdade de Ciências Médicas da Universidade Estadual de Campinas, Campinas, SP, Brasil
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Resumo

Os sarcomas musculoesqueléticos são doenças raras que exigem atenção. Frequentemente, apresentam alto grau de malignidade ao diagnóstico e se subestimados podem evoluir de forma agressiva local e sistemicamente. Apresentam-se como sarcoma de partes moles e sarcomas ósseos, sendo os de partes moles quatro a cinco vezes mais comuns. A maioria dos sarcomas de partes moles ocorre nos membros. Os subtipos mais comuns nas crianças e adolescentes são o rabdomiossarcoma e o sarcoma sinovial, nos adultos o sarcoma pleomórfico indiferenciado, lipossarcoma, leiomiossarcoma, mixofibrossarcoma e sarcoma sinovial; todos de alto grau de malignidade histológica. Muitos sarcomas de partes moles são confundidos com tumores benignos de partes moles, 100 vezes mais comuns, por isso são ressecados sem o planejamento necessário, acarretando em amputação de um membro que poderia ter sido preservado. Como em todos os cânceres, o fator prognóstico mais importante é a doença metastática. Na sua vigência, a taxa de sobrevida global cai em torno de 20 a 30%. As taxas de sobrevida no geral são parecidas entre os sarcomas ósseos e de partes moles, portanto o sarcoma de partes moles, além de mais prevalente, mostra-se tão agressivo quanto os sarcomas ósseos, por isso merece muita atenção dos ortopedistas que frequentemente são a primeira linha de atendimento dos portadores destes tumores.

Palavras-chave

epidemiologia - detecção precoce de cancer - metástase - neoplasia - tecido ósseo - fatores prognósticos - sarcoma de tecidos moles

∗ Trabalho desenvolvido no Departamento de Ortopedia e Traumatologia, Faculdade de Ciências Médicas da Universidade Estadual de Campinas (FCM-UNICAMP), Campinas, SP, Brasil.




Publikationsverlauf

Eingereicht: 24. September 2019

Angenommen: 20. Februar 2020

Artikel online veröffentlicht:
25. September 2020

© 2020. Sociedade Brasileira de Ortopedia e Traumatologia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commecial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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