CC BY-NC-ND 4.0 · Rev Bras Ortop (Sao Paulo) 2021; 56(04): 419-424
DOI: 10.1055/s-0040-1712136
Artigo de Atualização
Oncologia

Extremities Soft Tissue Sarcomas, more Common and as Dangerous as Bone Sarcomas[]

Article in several languages: português | English
1  Departamento de Ortopedia e Traumatologia, Faculdade de Ciências Médicas da Universidade Estadual de Campinas, Campinas, SP, Brasil
,
2  Instituto de Ortopedia e Traumatologia, Hospital das Clinicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brasil
,
1  Departamento de Ortopedia e Traumatologia, Faculdade de Ciências Médicas da Universidade Estadual de Campinas, Campinas, SP, Brasil
› Author Affiliations

Abstract

Musculoskeletal sarcomas are rare diseases that require attention. They often present high degree of malignancy at diagnosis and, if underestimated, they can evolve aggressively locally and systemically. They present as soft tissue sarcoma and bone sarcomas, with soft tissue being four to five times more common. Most soft tissue sarcomas occur in the extremities. The most common subtypes in children and adolescents are rhabdomyosarcoma and synovial sarcoma; in adults, undifferentiated pleomorphic sarcoma, liposarcoma, leiomyosarcoma, myxofibrosarcoma and synovial sarcoma; all with a high degree of histological malignancy. Many soft tissue sarcomas are confused with benign soft tissue tumors, 100 times more common, so they are resected without the necessary planning, resulting in amputation of a limb that could have been preserved. As in all cancers, the most important prognostic factor is metastatic disease. When it is present, the overall survival rate falls around 20 to 30%. Survival rates are generally similar between bone and soft tissue sarcomas. So soft tissue sarcomas, in addition to being more prevalent, are as aggressive as bone sarcomas, deserving a lot of attention from orthopedic surgeons, who are often the first line of care of carriers of these tumors.

Work developed in the Department of Orthopedics and Traumatology, Faculdade de Ciências Médicas da Universidade Estadual de Campinas (FCM-UNICAMP), SP, Brazil.




Publication History

Received: 24 September 2019

Accepted: 20 February 2020

Publication Date:
25 September 2020 (online)

© 2020. Sociedade Brasileira de Ortopedia e Traumatologia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commecial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

Thieme Revinter Publicações Ltda.
Rua do Matoso 170, Rio de Janeiro, RJ, CEP 20270-135, Brazil