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Patient Reported Outcome and cosmetic evaluation following implant-based breast-reconstruction with a titanized polypropylene mesh (TiLOOP® Bra): a prospective clinical study in 269 patients
Zielsetzung Implant-based or expander-supported breast reconstruction is an established surgical method. In a prospective, single-arm, multi-center study the patient reported outcome (PRO) after breast reconstruction with a synthetic surgical mesh was investigated. The focus of this study was the analysis of patient reported outcome 12 months after breast reconstruction.
Materialien und Methoden Primary or secondary implant-based breast reconstruction with support of a titanium-coated polypropylene mesh (TiLOOP® Bra) was performed in 269 patients in the course of the PRO-BRA study. Patient reported outcome 12 months after breast reconstruction was evaluated using the established Breast-Q questionnaire. Cosmetic outcome was evaluated by two independent experts.
Ergebnisse The Breast-Q and 12 months FU were completed by 210 women. Patients without AE had a significantly higher Breast-Q score for “sexual well-being”; “psychosocial well-being” was negatively influenced by prior therapies, and patients > 40 years had significantly lower scores at 12 months FU for “ satisfaction with breasts (SwB)” while the opposite was true for patients ≤ 40 years. The BMI only influenced PRO preoperatively. Unilateral surgery resulted in reduced “satisfaction with breast”; a higher UICC stadium (II-IV) resulted in worse “SwB”. Radiotherapy negatively influenced “SwB”. The cosmetic evaluation showed a significant difference in the evaluation by the patients and experts with the patients’ assessment being worse.
Zusammenfassung Our trial showed that two years after implant-based breast reconstruction with support of TiLOOP® Bra PRO is influenced by different factors. This information can be used to improve the decision-making process for women who chose implant-based breast reconstruction.
24 June 2020 (online)
© Georg Thieme Verlag KG
Stuttgart · New York