Journal of Pediatric Epilepsy 2020; 09(02): 051-052
DOI: 10.1055/s-0040-1710585
Case Report
Georg Thieme Verlag KG Stuttgart · New York

Severe Bilateral Cervical Lymphadenomegaly Associated with Ethosuximide

1  Department of Neurology, University of Campinas, Campinas, Sao Paulo, Brazil
,
Izilda A. Cardinalli
2  Department of Oncology, Boldrini Children's Center, Campinas, Sao Paulo, Brazil
,
Camila Maia Martin Daiggi
2  Department of Oncology, Boldrini Children's Center, Campinas, Sao Paulo, Brazil
› Author Affiliations
Funding None.
Further Information

Publication History

26 February 2020

15 April 2020

Publication Date:
12 May 2020 (online)

Abstract

Lymphadenomegaly associated with antiepileptic drugs is well documented; however, severe lymphadenopathy mimicking a neoplasm is a rare adverse event associated with antiepileptic drugs. It is usually characterized by a large cervical mass associated with fever, weight loss, skin rash, and abnormal complete blood count (atypical lymphocytes, eosinophilia, and abnormal neutrophil count). In this case report, we described a child with severe bilateral cervical lymphadenomegaly associated with ethosuximide, in which excisional biopsy of the enlarged nodes was needed to establish the final diagnosis. Prognosis was excellent after drug discontinuation.