Keynote Prescription in Homoeopathy: A Prospective Series of Fifteen Consecutive Cases
26 June 2020 (online)
Background Homoeopathy is a system of therapeutics which has a holistic approach towards diseased individual. Prescription in homoeopathy is based on individualisation which can be achieved in various ways. Keynote method is one of such various ways of prescription which needs to be validated by documentation of adequate and valid evidences in its favour.
Methods This article presents a series of 15 consecutive cases in which prescriptions were made on the basis of keynote. The outcome was assessed using Outcome Related to Impact on Daily Living (ORIDL) and Measure Yourself Medical Outcome Profile (MYMOP-2) scale. Modified Naranjo criteria were used to find out any possible causal attribution.
Result The results reflected improvement in ORIDL scale (+2 and +3). MYMOP-2 for Symptom 1 showed reduction in mean score from 5.60 (standard deviation [SD]: 0.63) to 2.67 (SD: 0.72) after a treatment period of 6 weeks. The reduction was statistically significant (mean difference 2.93 with 95% confidence interval: 2.6–3.2, t-score 19.1382, p < 0.001, paired t-test). The score of Modified Naranjo criteria ranged from 6 to 9. Thus these 15 cases derived the adequate subjective evidences in favour of keynote prescription. Further documentation and studies are warranted.
Informed consent has been obtained from all the patients for publication of this case series.
- 1 World Health Organization. WHO Global Report on Traditional and Complementary Medicine 2019. [eBook]. Luxembourg: World Health Organization; 2019 . [cited 2020 Feb 1]. Available from: https://www.who.int/traditional-complementary-integrative-medicine/WhoGlobalReportOnTraditionalAndComplementaryMedicine2019.pdf?ua=1
- 2 World Health Organization. Safety issues in the preparation of homeopathic medicines. [eBook]. Spain: World Health Organization; 2009 . [cited 2020 Feb 1]. Available from: https://www.who.int/medicines/areas/traditional/Homeopathy.pdf
- 3 Manchanda RK. , Ed. Scientific framework of homeopathy evidence based medicine. Revised edition after 71st LMHI congress, Aug 2016. [eBook]. Liga Medicorum Homoeopathica Internationalis; 2017 . [cited 2020 Feb 1]. Available from: http://www.lmhi.org/downloads/documents/LMHI%20Sc%20framework%202016-modi.pdf
- 4 Hahnemann CFS. . Organon of Medicine. Boericke W, translator. 6th ed. New Delhi: B Jain Publishers (P) Ltd; 2012
- 5 Kumar SP. Different types of prescription. HomoeoTimes 2004 10(01). Available from: http://www.homoeotimes.com/archive/autpraveen.htm
- 6 Guernsey HN. The “Key-note” system. The Hahnemannian Monthly. 1868; 3 (12) 561-569
- 7 Mathur KN. . Principles of Prescribing: Collected from Clinical Experiences of Pioneers of Homoeopathy. New Delhi: B Jain Publishers (P) Ltd; 2002
- 8 Chitkara HL. . compiler. Best of Burnett. New Delhi: B Jain Publishers (P) Ltd; 2002
- 9 Allen HC. Keynotes and Characteristics with Comparison of Some of the Leading Remedies of the Materia Medica with Bowel Nosodes. 15th impression. New Delhi: B Jain Publishers (P) Ltd; 2016
- 10 Sharma S, Wadhwani GG. Experience with homoeopathy in a case of large urethral calculus. Indian J Res Homoeopathy 2013; 7 (04) 176-180
- 11 Klein-Laansma CT, Rutten ALB, Jansen JPCH, van Wietmarschen H, Jong MC. Evaluation of a prognostic homeopathic questionnaire for women with premenstrual disorders. Complement Med Res 2018; 25 (03) 173-182
- 12 El-Gilany AH. What is case series. Asp Biomed Clin Case Rep. 2018; 1 (01) 10-15
- 13 Murad MH, Sultan S, Haffar S, Bazerbachi F. Methodological quality and synthesis of case series and case reports. BMJ Evid Based Med 2018; 23 (02) 60-63
- 14 Reilly D, Mercer SW, Bikker AP, Harrison T. Outcome related to impact on daily living: preliminary validation of the ORIDL instrument. BMC Health Serv Res 2007; 7: 139 . Doi: 10.1186/1472-6963-7-139
- 15 Paterson C, Britten N. In pursuit of patient-centred outcomes: a qualitative evaluation of the ‘Measure Yourself Medical Outcome Profile’. J Health Serv Res Policy 2000; 5 (01) 27-36
- 16 van Haselen RA. Homeopathic clinical case reports: development of a supplement (HOM-CASE) to the CARE clinical case reporting guideline. Complement Ther Med 2016; 25: 78-85
- 17 Hering C. The Guiding Symptoms of Our Materia Medica. Philadelphia: American Homoeopathic Publishing Society; 1879. . Vol 1 to 10.
- 18 Guernsey JC. , Ed. Keynote to the Materia Medica as taught by Henry N. Guernsey. Philadelphia: Hahnemann Publishing House; 1887
- 19 Singh S. Prescription on Keynote Symptoms or Keynote Method of Prescription. In: Dictionary and helps for further study of Allen's keynotes. 2nd ed. Kolkata: Homoeopathic publications; 2015: 4-7
- 20 Kent JT. . Lesser Writings, Clinical Cases, New Remedies, Aphorisms and Precepts. New Delhi: B Jain Publishers (P) Ltd; 2002
- 21 Close S. The Genius of Homoeopathy. New Delhi: IBP Publishers; 2011
- 22 Thompson E, Viksveen P, Barron S. A patient reported outcome measure in homeopathic clinical practice for long-term conditions. Homeopathy 2016; 105 (04) 309-317
- 23 Polus BI, Kimpton AJ, Walsh MJ. Use of the measure your medical outcome profile (MYMOP2) and W-BQ12 (Well-Being) outcomes measures to evaluate chiropractic treatment: an observational study. Chiropr Man Therap 2011; 19: 7 . Doi: 10.1186/2045-709X-19-7
- 24 Naranjo CA, Busto U, Sellers EM. , et al. A method for estimating the probability of adverse drug reactions. Clin Pharmacol Ther 1981; 30 (02) 239-245