Journal of Pediatric Neurology
DOI: 10.1055/s-0040-1709461
Case Report
Georg Thieme Verlag KG Stuttgart · New York

Concomitant Congenital Horner and Harlequin Syndromes: Case Report and Review of Literature

Ayman G. Elnahry
1  Department of Ophthalmology, Faculty of Medicine, Cairo University, Cairo, Egypt
,
Aisha A. Gamal Eldin
2  Department of Child Health, The American International School in Egypt, Cairo, Egypt
,
Aya G. Elnahry
3  School of Medicine, New Giza University, Giza, Egypt
,
Gehad A. Elnahry
1  Department of Ophthalmology, Faculty of Medicine, Cairo University, Cairo, Egypt
› Author Affiliations
Funding None.
Further Information

Publication History

30 January 2020

25 February 2020

Publication Date:
17 April 2020 (online)

Abstract

Harlequin syndrome is a condition characterized by autonomic dysfunction leading to hemifacial flushing on one side with pallor and impaired sweating on the other side. It is a rare condition that can be both congenital and acquired, with congenital cases being rarer, comprising ∼6% of all Harlequin syndrome cases. Harlequin syndrome is usually associated with other autonomic disturbances including Horner syndrome especially when presenting as a congenital condition. We reported the findings of a rare case of concomitant congenital Horner and Harlequin syndromes in an otherwise healthy 4-month-old male infant patient and provided a review of the current literature.

Ethical Approval

This report was approved by Cairo University Research Ethics Committee and followed the tenets of the Declaration of Helsinki.


Note

The patient's parents signed an informed consent to publish this information.