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CC BY-NC-ND 4.0 · Int Arch Otorhinolaryngol 2021; 25(02): e200-e204
DOI: 10.1055/s-0040-1709197
Original Research

Effect of Vitiligo on Auditory Functions: Is There Any Association?

Vishal Singh
1   Department of ENT, Indira Gandhi Medical College, Shimla, Himachal Pradesh, India
,
Trilok C. Guleria 
1   Department of ENT, Indira Gandhi Medical College, Shimla, Himachal Pradesh, India
,
Ramesh K. Azad
1   Department of ENT, Indira Gandhi Medical College, Shimla, Himachal Pradesh, India
,
Narender K. Mohindroo
1   Department of ENT, Indira Gandhi Medical College, Shimla, Himachal Pradesh, India
,
Devraj Sharma
1   Department of ENT, Indira Gandhi Medical College, Shimla, Himachal Pradesh, India
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Abstract

Introduction Vitiligo is an acquired pigmentary disorder of unknown etiology, clinically characterized by whitish macules caused by selective loss of melanocytes. There are many melanocytes in the human cochlea. Recent studies have suggested a direct relation between cochlear dysfunction and decreased amounts of melanin.

Objective To determine the effect of vitiligo on auditory function.

Methods The present prospective, case control study was performed over a period of 1 year in patients between 15 and 40 years old with nonsegmental disease and the same number of controls. Pure tone audiometry (PTA) and Otoacoustic emission (OAE) were performed to analyze the correlation between vitiligo and auditory function.

Results The mean pure tone audiometric threshold in the right ear at 0.5, 8 kHz, and in the left ear at the frequency of 8 kHz in the case group were significantly higher as compared with controls. The average band reproducibility (%) in the right and left ear of controls was significantly higher at the frequency of 4 kHz as compared with cases. It has been observed that signal to noise ratio was statistically higher at the frequency of 5kHz in the right ear and at 2, 3, and 5kHz in the left ear in controls as compared with cases. On the basis of disease type and duration of disease; mean pure tone audiometric threshold, average band reproducibility and signal to noise ratio, no significant effect was observed in the present study.

Conclusion Vitiligo has an effect on cochlear function irrespective of the duration or distribution of the disease.

Keywords

vitiligo - stria vascularis - nonsegmental - audiometric - auditory defect


Publikationsverlauf

Eingereicht: 30. Mai 2019

Angenommen: 25. Februar 2020

Artikel online veröffentlicht:
23. Juni 2020

© 2020. Fundação Otorrinolaringologia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commecial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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