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CC BY-NC-ND 4.0 · Journal of Health and Allied Sciences NU 2016; 06(04): 04-09
DOI: 10.1055/s-0040-1708667
Original Article

Antibiotic Sensitivity and Evaluation of Plasmid Profile of Major Foodborne Pathogens

Ibikunle Ibitayo Anibijuwon
1   Lecturers, Department of Microbiology, Faculty of Life Sciences, University of Ilorin, Ilorin, Nigeria
,
Ifeoluwa Deborah Gbala
2   Postgraduate Student, Department of Microbiology, Faculty of Life Sciences, University of Ilorin, Ilorin, Nigeria
,
Jumai Adeola Abioye
3   Lecturers, Department of Microbiology, Faculty of Life Sciences, University of Ilorin, Ilorin, Nigeria
,
Paul Oluwaseun Ogunlade
4   Graduate Student, Department of Microbiology, Faculty of Life Sciences, University of Ilorin, Ilorin, Nigeria
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Abstract

This study revealed the reason behind the antibiotics resistance of isolated food-borne pathogens through their susceptibility testing to various antibiotics of choice. The results of the study revealed that resistance of the bacteria isolates which are Streptococcus sp., Staphylococcus aureus, Proteus vulgaris, Shigella sp., Escherichia coli, Pseudomonas aeruginosa, Bacillus sp. to different antibiotics varies and differs considerably. For instance, Pseudomonas aeruginosa showed resistance to Amoxicillin, Augmentin, Gentamicin and Tetracycline. Staphylococcus sp. isolated showed multiple resistances to Cloxacillin, Erythromycin, Amoxicillin, Augmentin and Gentamicin. Proteus vulgaris showed multiple resistances to five antibiotics in-vitro which are Augmentin, Nitrofurantoin, Amoxicillin, Cotrimoxazole and Nalidixic. The seven isolates were then assayed for plasmid profiling by agarose gel electrophoresis. All the isolates has plasmid with varying sizes of between 9–21kb. Further conjugative study will reveal more reason behind the resistance.

Keywords

Antibiotics - Resistance - Susceptibility - Plasmid


Publication History

Received: 21 March 2016

Accepted: 02 November 2016

Article published online:
22 April 2020

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