J Pediatr Intensive Care 2020; 09(03): 207-209
DOI: 10.1055/s-0040-1708556
Original Article
Georg Thieme Verlag KG Stuttgart · New York

Effect of Phototherapy on Stroke Volume in Newborn Infants with Jaundice

Majid Firouzi
1   Department of Pediatrics, Faculty of Medicine, Lorestan University of Medical Sciences, Khorramabad, Iran
,
Hamidreza Sherkatolabbasieh
1   Department of Pediatrics, Faculty of Medicine, Lorestan University of Medical Sciences, Khorramabad, Iran
,
Alireza Nezami
1   Department of Pediatrics, Faculty of Medicine, Lorestan University of Medical Sciences, Khorramabad, Iran
,
Shiva Shafizadeh
2   Department of Internal Medicine, Lorestan University of Medical Sciences, Khorramabad, Iran
› Author Affiliations
Further Information

Publication History

30 November 2019

18 February 2020

Publication Date:
07 April 2020 (online)

Abstract

One of the rare complications associated with phototherapy include redistribution of blood flow that can alter cardiac output in infants. The aim of this study was to evaluate the effects of phototherapy on left ejection fraction in infants with jaundice. Twenty-nine infants admitted in Shahid Madani Children Hospital for receiving phototherapy were included in this study. Echocardiography was performed in the participants, immediately before and 24 hours after the treatment. Nineteen infants were reported to have decrease in the stroke volume following the treatment. The mean levels of stroke volume before and after phototherapy were 6.99 ± 2.17 and 6.55 ± 1.85 L/m2, respectively (p = 0.011). Phototherapy can reduce left ejection fraction in newborn infants with hyperbilirubinemia.

Authors' Contributions

M.F. and H.S. conceptualized and designed the study, drafted the initial manuscript, and reviewed and revised the manuscript. A.N. designed the data collection instruments, collected data, performed the initial analyses, and reviewed and revised the manuscript. S.S. coordinated and supervised data collection and critically reviewed the manuscript for important intellectual content.


 
  • Reference

  • 1 Ullah S, Rahman K, Hedayati M. Hyperbilirubinemia in neonates: types, causes, clinical examinations, preventive measures and treatments: a narrative review article. Iran J Public Health 2016; 45 (05) 558-568
  • 2 Muñoz-Hoyos A, Jaldo-Alba F, Molina-Carballo A, Rodríguez-Cabezas T, Molina-Font JA, Acuña-Castroviejo D. Absence of plasma melatonin circadian rhythm during the first 72 hours of life in human infants. J Clin Endocrinol Metab 1993; 77 (03) 699-703
  • 3 American Academy of Pediatrics Subcommittee on Hyperbilirubinemia. Management of hyperbilirubinemia in the newborn infant 35 or more weeks of gestation. Pediatrics 2004; 114 (01) 297-316
  • 4 Ahmadipour S, Mardani M, Mohsenzadeh A, Baharvand P, Nazeri MG. The lowering of bilirubin levels in full-term newborns by the effect of combined massage therapy and phototherapy practice. Am J Perinatol 2019
  • 5 Martin RJ, Fanaroff AA, Walsh MC. Fanaroff and Martin's Neonatal-Perinatal Medicine E-Book: Diseases of the Fetus and Infant. 9th ed. Philadelphia, PA: Saunders-Elsevier; 2010
  • 6 Kliegman RM, Behrman RE, Jenson HB, Stanton BM. Nelson textbook of pediatrics e-book. 18th ed. Philadelphia, PA: Saunders-Elsevier; 2007
  • 7 Benders MJ, van Bel F, van de Bor M. Haemodynamic consequences of phototherapy in term infants. Eur J Pediatr 1999; 158 (04) 323-328
  • 8 Hansen TW. Prevention of neurodevelopmental sequelae of jaundice in the newborn. Dev Med Child Neurol 2011; 53 (Suppl. 04) 24-28
  • 9 Xiong T, Tang J, Mu DZ. [Side effects of phototherapy for neonatal hyperbilirubinemia]. Zhongguo Dang Dai Er Ke Za Zhi 2012; 14 (05) 396-400
  • 10 Ahmadipour S, Baharvand P, Rahmani P, Hasanvand A, Mohsenzadeh A. Effect of synbiotic on the treatment of jaundice in full term neonates: a randomized clinical trial. Pediatr Gastroenterol Hepatol Nutr 2019; 22 (05) 453-459
  • 11 Bader D, Kugelman A, Blum DE, Riskin A, Tirosh E. Effect of phototherapy on cardiorespiratory activity during sleep in neonates with physiologic jaundice. Isr Med Assoc J 2006; 8 (01) 12-16
  • 12 Taee N, Tarhani F, Goodarzi MF, Safdari M, Bajelan A. Mermaid syndrome: a case report of a rare congenital anomaly in full-term neonate with thumb deformity. AJP Rep 2018; 8 (04) e328-e331
  • 13 Lakshminrusimha S. The pulmonary circulation in neonatal respiratory failure. Clin Perinatol 2012; 39 (03) 655-683
  • 14 Benders MJ, van Bel F, van de Bor M. The effect of phototherapy on renal blood flow velocity in preterm infants. Biol Neonate 1998; 73 (04) 228-234
  • 15 Tarhani F, Nezami A. Role of probiotics in treatment of congenital heart disease and necrotizing enterocolitis. PharmaNutrition 2019; 8: 100144
  • 16 Ghafarzadeh M, Namdari P, Tarhani M, Tarhani F. A review of application of stem cell therapy in the management of congenital heart disease. J Matern Fetal Neonatal Med 2020; 33 (09) 1607-1615
  • 17 Doyle J, Schmitdt B, Avery GB, Fletcher MA, Macdonald MG. , eds. Neonatology, Pathophysiology Management of the Newborn. 5th ed. Philadelphia, PA: Lippincott; 1999
  • 18 Wackers FJ, Russo DJ, Russo D, Clements JP. Prognostic significance of normal quantitative planar thallium-201 stress scintigraphy in patients with chest pain. J Am Coll Cardiol 1985; 6 (01) 27-30
  • 19 Javorka K, Zavarská L. [Changes in systemic blood pressure and cardiorespiratory parameters in premature neonates during phototherapy] (in Slovak). Cesk Pediatr 1990; 45 (04) 230-232
  • 20 Jahnukainen T, Lindqvist A, Jalonen J, Kero P, Välimäki I. Responsiveness of cutaneous vasculature to thermal stimulation during phototherapy in neonatal jaundice. Eur J Pediatr 1999; 158 (09) 757-760
  • 21 Benders MJ, Van Bel F, Van de Bor M. Cardiac output and ductal reopening during phototherapy in preterm infants. Acta Paediatr 1999; 88 (09) 1014-1019
  • 22 Benders MJ, van Bel F, van de Bor M. The effect of phototherapy on cerebral blood flow velocity in preterm infants. Acta Paediatr 1998; 87 (07) 786-791
  • 23 Yao AC, Martinussen M, Johansen OJ, Brubakk AM. Phototherapy-associated changes in mesenteric blood flow response to feeding in term neonates. J Pediatr 1994; 124 (02) 309-312
  • 24 Pezzati M, Biagiotti R, Vangi V, Lombardi E, Wiechmann L, Rubaltelli FF. Changes in mesenteric blood flow response to feeding: conventional versus fiber-optic phototherapy. Pediatrics 2000; 105 (02) 350-353