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CC BY-NC-ND 4.0 · AJP Rep 2020; 10(01): e106-e112
DOI: 10.1055/s-0040-1708487
Original Article
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Efficacy of Prophylactic Antibiotics in Bakri Intrauterine Balloon Placement: A Single-Center Retrospective Analysis and Literature Review

Authors

  • Yoshikazu Nagase

    1   Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Osaka, Japan

  • Shinya Matsuzaki 

    1   Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Osaka, Japan

  • Yoko Kawanishi

    1   Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Osaka, Japan

  • Satoshi Nakagawa

    1   Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Osaka, Japan

  • Aiko Kakigano

    1   Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Osaka, Japan

  • Tsuyoshi Takiuchi

    1   Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Osaka, Japan

  • Kazuya Mimura

    1   Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Osaka, Japan

  • Takuji Tomimatsu

    1   Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Osaka, Japan

  • Masayuki Endo

    1   Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Osaka, Japan
    2   Department of Children and Women's Health, Osaka University Graduate School of Medicine, Osaka, Japan

  • Tadashi Kimura

    1   Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Osaka, Japan
Weitere Informationen

Publikationsverlauf

19. Oktober 2019

15. November 2019

Publikationsdatum:
19. März 2020 (online)

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Abstract

Objective Bakri intrauterine balloon (BIUB) placement is an effective treatment for postpartum hemorrhage (PPH). This study aims to evaluate the risk of infection during BIUB placement.

Study Design Data for all deliveries (n = 2,144) at our institution between January 2014 and March 2018 were retrospectively reviewed. Patients diagnosed with PPH (n = 758) were included in our analysis, further divided into BIUB (n = 80) and non-BIUB groups (n = 678), and subdivided into vaginal delivery (VD), elective cesarean delivery (CD), and emergency CD groups. Postpartum endometritis rate was compared in each group. A single dose of prophylactic antibiotics was administered for BIUB placement in the VD group. In the CD groups, antibiotics were administered preoperatively once, and no additional antibiotics for BIUB placement were administered. To obtain an antibiotics administration protocol to be applied during BIUB placement, we electronically searched the PubMed and Scopus databases.

Results No significant differences were observed in endometritis rates between BIUB and non-BIUB groups of all groups. In the literature review, of 27 suitable publications identified, multiple doses of antibiotics were administered in 17 (62.9%) studies and none investigated the efficacy of a protocol for antibiotic.

Conclusion Our protocol might be effective and sufficient in preventing postpartum BIUB placement-related endometritis.

Keywords

Bakri balloon - balloon tamponade - complication - endometritis - prophylactic antibiotics - postpartum hemorrhage

Authors' Contribution

Y.N., S.M., Y.K., M.E., A.K., and T.T. contributed to study conception and design, data collection, and drafting of the manuscript. M.E., T.T., and T.K. investigated the articles identified in the literature search. A.K. performed an extensive revision of the revised manuscript. T.K. conceived the study, provided general supervision, helped draft the manuscript, and gave final approval for publication of the manuscript. All authors read and approved the final version of the manuscript.


Supplementary Material