Carbonylative Suzuki–Miyaura Coupling Reactions of Aryl Iodides with Readily Available Polymer-Immobilized Palladium Nanoparticles

Dedicated to Professor Barry M. Trost to celebrate his great contributions to organic synthesis

Abstract

Polysilane/alumina-supported palladium nanoparticle catalyzed carbonylative Suzuki–Miyaura coupling reactions under ligand-free conditions have been developed to synthesize diaryl ketones. High yields and selectivities were achieved even with low catalyst loading under atmospheric pressure of CO gas. A variety of aryl iodides and arylboronic acids could be utilized to afford the diaryl ketones in excellent yields. Moreover, the ligand-free immobilized palladium nanoparticles could be recovered by simple filtration and the catalytic activity could be maintained for several runs.

Key words

carbonylative Suzuki–Miyaura coupling - heterogeneous catalyst - palladium catalyst - nanoparticle - diaryl ketones

• References and Notes

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