Synlett
DOI: 10.1055/s-0040-1707243
cluster
© Georg Thieme Verlag Stuttgart · New York

Carbonylative Suzuki–Miyaura Coupling Reactions of Aryl Iodides with Readily Available Polymer-Immobilized Palladium Nanoparticles

Tomohiro Yasukawa
,
Zhiyuan Zhu
,
Yasuhiro Yamashita
,
This work was supported in part by a Grant-in-Aid for Scientific Research from JSPS, the University of Tokyo, and MEXT (Japan), JST.
Further Information

Publication History

Received: 27 May 2020

Accepted after revision: 10 July 2020

Publication Date:
26 August 2020 (online)


Dedicated to Professor Barry M. Trost to celebrate his great contributions to organic synthesis

Published as part of the Cluster The Power of Transition Metals: An Unending Well-Spring of New Reactivity

Abstract

Polysilane/alumina-supported palladium nanoparticle catalyzed carbonylative Suzuki–Miyaura coupling reactions under ligand-free conditions have been developed to synthesize diaryl ketones. High yields and selectivities were achieved even with low catalyst loading under atmospheric pressure of CO gas. A variety of aryl iodides and arylboronic acids could be utilized to afford the diaryl ketones in excellent yields. Moreover, the ligand-free immobilized palladium nanoparticles could be recovered by simple filtration and the catalytic activity could be maintained for several runs.

Supporting Information

 
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