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CC BY-NC-ND 4.0 · Journal of Health and Allied Sciences NU 2015; 05(02): 004-007
DOI: 10.1055/s-0040-1703879
Original Article

GENTAMICIN: MYTHS AND TRUTHS

Muralee Mohan
1   Professor, Department of Oral & Maxillofacial Surgery, A.B. Shetty Memorial Institute of Dental Sciences, Nitte University, Mangalore, Karnataka, India
,
Deepthi Shetty
2   Assistant Professors, Department of Oral & Maxillofacial Surgery, A.B. Shetty Memorial Institute of Dental Sciences, Nitte University, Mangalore, Karnataka, India
,
Tripthi Shetty
3   Assistant Professors, Department of Oral & Maxillofacial Surgery, A.B. Shetty Memorial Institute of Dental Sciences, Nitte University, Mangalore, Karnataka, India
,
Suman Banerjee
4   Post Graduate, Department of Oral & Maxillofacial Surgery, A.B. Shetty Memorial Institute of Dental Sciences, Nitte University, Mangalore, Karnataka, India
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Abstract

Gentamicin belongs to the group of antimicrobial agents, aminoglycosides. It is the prototype member of this group of antimicrobial agents that is utilized to treat various bacterial infections, mostly those caused by Gram negative bacteria. This is due to its irreversible binding to the 30S component of the ribosome. But the use of aminoglycosides and thus Gentamicin is limited owing to its profound adverse effects on the ear & the kidney. But proper calculation of the dosage can limit these side effects and prove to be an effective antimicrobial agent.

Keywords

Gentamicin - Dosage - nephrotoxicity


Publication History

Article published online:
22 April 2020

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