Abstract
The phytochemical and antimicrobial activity of the petroleum ether and crude methanol
extracts, chloroform and ethyl acetate fractions of the leaves of Lannea kerstingii were investigated. Phytochemical screening revealed the presence of steroids and
triterpenes in the petroleum ether extract, steroid, triterpene, flavonoids and tannins
in both crude methanol extract and chloroform fraction while the ethyl acetate fraction
contained only flavonoids and tannins. The extracts exhibited antimicrobial activities
with zones of inhibition ranging from 17.00 to 21.03, 20.10 to 25.24, 25.32 to 34.02
and 22.28 to 27.20 mm for petroleum ether extract, methanol extract, chloroform and
ethyl acetate fractions respectively. The minimum inhibitory concentration was between
5 and 10mg/ml, 5mg/ml for the petroleum ether and methanol extract respectively, and
between 2.5 and 5 mg/ml, 5mg/ml for the acetate fractions. The minimum bactericidal
concentration for all the extracts was 40mg/ml respectively except for chloroform
fraction which ranged from 20 to 40mg/ml. The minimum fungicidal concentration for
all the extracts was found to be 40mg/ml respectively. This result indicates the broad
spectrum antimicrobial potential of L. Kerstingii and justifies the use of this plant in traditional medicine.
Keywords
antimicrobial - phytochemical - barteri -
lannea kerstingii