CC BY-NC-ND 4.0 · Journal of Health and Allied Sciences NU 2011; 01(04): 10-15
DOI: 10.1055/s-0040-1703532
Original Article

EVALUATION OF EFFECT OF REUSED EDIBLE OILS ON VITAL ORGANS OF WISTAR RATS

Shastry C. S.
1  Department of Pharmacology, NGSM Institute of Pharmaceutical Sciences, Deralakatte, Mangalore - 575 018, India
,
Patel Narendrakumar Ambalal
1  Department of Pharmacology, NGSM Institute of Pharmaceutical Sciences, Deralakatte, Mangalore - 575 018, India
,
Joshi Himanshu
1  Department of Pharmacology, NGSM Institute of Pharmaceutical Sciences, Deralakatte, Mangalore - 575 018, India
,
Aswathanarayana B. J.
1  Department of Pharmacology, NGSM Institute of Pharmaceutical Sciences, Deralakatte, Mangalore - 575 018, India
› Author Affiliations
funding: This study received no specific grant from any funding agency in the public, commercial or not for profit sectors.

Abstract

Objective: Cooking oils (edible oils) are vegetable oils which are extensively used for cooking in India. These edible oils are rich in triglycerides, sterol, tocoferol, carotenes and pigments. Upon frying, edible oils gives rise to formation of free radicals and other harmful agents. The degraded products of oils generated while cooking produce unfavorable effects. The present study was designed to evaluate the effects of reused edible oils (sunflower oil and palm oil) on vital organs of experimental animals.

Materials and Methods: Wistar rats were fed fresh and reused edible oils - sunflower oil and palm oil (15 gm oil/100gm of feed consumed) and control group received normal food and water for a period of 8 weeks. The parameters studied include changes in physicochemical properties of reused oils, change in body weight of animals, plasma lipid profile, biochemical parameters and histopathological examination.

Results: The result showed the change in physicochemical characteristics of reused oils. The animals fed with fresh and reused palm oil significant increase the body weight while reused sunflower oil fed group showed decrease significantly. The biochemical parameters, SGPT (serum glutamate–pyruvate transaminase), SGOT (serum glutamate- oxaloacetate transaminase), and ALP (alkaline phoshphatase) were increased in reused oils fed groups. The histopathological study showed the change in size of liver, heart, kidney and testes cells in reused oil groups.

Conclusions: From the present study, it can be concluded that reused sunflower oil and palm oil, can be toxic and can cause considerable damage to the vital organs of the experimental animals.



Publication History

Publication Date:
04 May 2020 (online)

© .

Thieme Medical and Scientific Publishers Private Ltd.
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  • References

  • 1 Mukherjee S, Mitra A. Health Effects of Palm Oil. J Hum Ecol 2009; 26(3): 197-203.
  • 2 Kokate CK. Pharmacognosy, 11th edn. Nirali Prakashan, Pune. pp. 227-61.
  • 3 Quiles JL, Huertas JR, Battino M, Tortosa MC, Cassinello M, Mataix J, et al. The intake of fried virgin olive or sunflower oils differentially induces oxidative stress in rat liver microsomes. Br J Nutr 2002; 88(1): 57-65.
  • 4 Ramachandran HD, Narasimhamurthy K, Raina PL. Effect of oxidative stress on serum and antioxidant enzymes in liver and kinder of rats and their modulation through dietary factors. Ind J Experi Biol 2002; 40: 1010-5
  • 5 Plummer DT. An introduction to practical Biochemistry, 3rd edn. 1971; McGraw-Hill, UK. pp. 195-9.
  • 6 Godkar PB. Text Book of Medical Laboratory Technology, 1994; Bhalani publishing house, Mumbai. pp. 118,122,140,186,203,437.
  • 7 Henry RJ. Clinical Chemistry. Principles and Techniques, 2nd Edn. 1974; Harper and Row. pp. 822, 1974.
  • 8 Osim E, Owu E, Isong V. Influence of chromic consumption of thermoxidized and fresh palm oil diets on basal metabolic rats, body weight and morphology of tissues in rats. Discov Innov 1994; 6: 384-96.
  • 9 Boatella RJ, Codony R, Rafecas M, Guardiala F. Recycled cooking oils: assesment of risks for public health. European parliament directorate general for research directorate, The STOA Programme 2000; PE 289.889 / Fin. St
  • 10 Donelly JK, Robinson DS. Free radicals in foods. Free Radical Res 1995; 22: 147–76.
  • 11 Srivastava S, Singh M, George J, Bhui K, Shuklav Y. Genotoxic and carcinogenic risks associated with the consumption of repeatedly boiled sunflower oil. J Agric Food Chem 2010; 58 (20): 11179-86.
  • 12 Aruna K, Rukkumani R, Sureshvarma P. Role of an aminothiazole derivative on ethonal and thermally oxidized sunflower oil – induced toxicity. Polish J pharmacol 2004; 56: 233-40.