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CC BY-NC-ND 4.0 · Journal of Health and Allied Sciences NU 2011; 01(04): 10-15
DOI: 10.1055/s-0040-1703532
Original Article

EVALUATION OF EFFECT OF REUSED EDIBLE OILS ON VITAL ORGANS OF WISTAR RATS

Shastry C. S.
1   Department of Pharmacology, NGSM Institute of Pharmaceutical Sciences, Deralakatte, Mangalore - 575 018, India
,
Patel Narendrakumar Ambalal
1   Department of Pharmacology, NGSM Institute of Pharmaceutical Sciences, Deralakatte, Mangalore - 575 018, India
,
Joshi Himanshu
1   Department of Pharmacology, NGSM Institute of Pharmaceutical Sciences, Deralakatte, Mangalore - 575 018, India
,
Aswathanarayana B. J.
1   Department of Pharmacology, NGSM Institute of Pharmaceutical Sciences, Deralakatte, Mangalore - 575 018, India
› Author Affiliations funding: This study received no specific grant from any funding agency in the public, commercial or not for profit sectors.
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Abstract

Objective: Cooking oils (edible oils) are vegetable oils which are extensively used for cooking in India. These edible oils are rich in triglycerides, sterol, tocoferol, carotenes and pigments. Upon frying, edible oils gives rise to formation of free radicals and other harmful agents. The degraded products of oils generated while cooking produce unfavorable effects. The present study was designed to evaluate the effects of reused edible oils (sunflower oil and palm oil) on vital organs of experimental animals.

Materials and Methods: Wistar rats were fed fresh and reused edible oils - sunflower oil and palm oil (15 gm oil/100gm of feed consumed) and control group received normal food and water for a period of 8 weeks. The parameters studied include changes in physicochemical properties of reused oils, change in body weight of animals, plasma lipid profile, biochemical parameters and histopathological examination.

Results: The result showed the change in physicochemical characteristics of reused oils. The animals fed with fresh and reused palm oil significant increase the body weight while reused sunflower oil fed group showed decrease significantly. The biochemical parameters, SGPT (serum glutamate–pyruvate transaminase), SGOT (serum glutamate- oxaloacetate transaminase), and ALP (alkaline phoshphatase) were increased in reused oils fed groups. The histopathological study showed the change in size of liver, heart, kidney and testes cells in reused oil groups.

Conclusions: From the present study, it can be concluded that reused sunflower oil and palm oil, can be toxic and can cause considerable damage to the vital organs of the experimental animals.

Keywords

Edible oils - sunflower oil - palm oil - free radicals


Publication History

Article published online:
04 May 2020

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