Abstract
Necrobiotic xanthogranuloma is a rare granulomatous disease involving skin and subcutaneous
tissues. A 61 year old woman presented with a 5 year history of enlarging plaques
around both eyelids.it was associated with diminished vision in both eyes. The lesions
are often bilateral,symmetrical and ophthalmologic complications are observed. A histopathological
examination showed features of necrobiotic xanthogranuloma. Necrobiotic xanthogranuloma
is usually associated with paraproteinemia which was not seen in our case.The pathogenesis
remains unclear. Although there is no first line of treatment, reports have shown
variable benefits with chemotherapeutic agent and steroids.
Keywords
necrobiotic xanthogranuloma - necrobiosis
