EFFECT OF ELECTRON BEAM RADIATION ON HEMATOPOIETIC CELLS OF SWISS ALBINO MICE

Suchetha Kumari N; Madhu L.N

doi:10.1055/s-0040-1703513

Journal of Health and Allied Sciences NU, Inhaltsverzeichnis

CC BY-NC-ND 4.0 · Journal of Health and Allied Sciences NU 2011; 01(01/03): 15-18
DOI: 10.1055/s-0040-1703513

Original Article

EFFECT OF ELECTRON BEAM RADIATION ON HEMATOPOIETIC CELLS OF SWISS ALBINO MICE

Suchetha Kumari N

Department of Biochemistry, K.S. Hegde Medical Academy, Nitte University, Mangalore

,

Madhu L.N

Central Research Laboratory, Nitte University, Mangalore

› Institutsangaben

Abstract

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Abstract

Ionizing radiation which results in the free radical formation and it leads to damage of biological macromolecules such as DNA, proteins, lipids. 36 male Swiss albino mice were used for survival assay, to find out the lethal dose of Electron Beam Radiation. It was found to be 10Gy was the lethal dose for mice. Different dosages (4Gy, 6Gy and 8Gy) of electron beam radiation were used to study the micronucleus formation in irradiated mice. The results showed micronucleus formation will increase linearly with radiation dosage.

Keywords

Electron beam radiation - LD₅₀ - Micronucleus

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Referenzen

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