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Journal of Pediatric Neurology 2021; 19(03): 166-172
DOI: 10.1055/s-0040-1701637
Original Article

Comparison of Health-Related-Quality-of-Life among Children with Epilepsy and a Healthy Control Group in Tehran

Morteza Abdollahi    *
1   Social Determinants of Health Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
,
Mohsen Abbasi-Kangevari    *
1   Social Determinants of Health Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
,
Ali-Asghar Kolahi 
1   Social Determinants of Health Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
,
Ahmad-Reza Farsar 
1   Social Determinants of Health Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
› Author Affiliations Funding None
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Abstract

The objective of this study was to determine the quality-of-life (QoL) among children with epilepsy in comparison with a healthy control group. Participants included mothers of 206 children with epilepsy and of 211 healthy controls. The QoL was measured via cross-cultural adaptation of the Quality-of-Life in Children with Epilepsy Questionnaire, which was also modified for the control group. The mean (standard deviation) overall QoL score of children with epilepsy was lower than that of the healthy control group at: 74.3 (8.2) versus 87.9 (6.6), p < 0.001. In addition, all seven dimensions of QoL were lower among children with epilepsy compared with that of the healthy control group. The health-related QoL of children with epilepsy was lower than that of the healthy control group. Children experiencing seizures more frequently, experiencing side effects from antiepileptic drugs, having a history of hospitalization, and having poor school performance displayed lower scores in QoL, which may highlight the impact of the severity of the disease and proper management of seizures on the quality-of-life in children with epilepsy.

Keywords

epilepsy - quality of life - seizure

Ethics Approval and Consent to Participate

The study was approved by the Ethical Committee of Shahid Beheshti University of Medical Sciences under the reference code IR.SBMU.RETECH.REC.1398.468. Informed consent for participants was obtained from all individual participants included in the study.


Availability of Data and Materials

The data that support the findings of this study are available at Shahid Beheshti University of Medical Sciences but restrictions apply to these data, which were used under license for the current study, making them unavailable to the public. Data are however, accessible through the authors upon reasonable request and with permission of Shahid Beheshti University of Medical Sciences.


Authors' Contributions

A.A.K. hypothesized the idea, supervised the data collection and interpretation, drafted and revised the manuscript. M.A. and A.R.F. hypothesized the idea and drafted the manuscript. M.A-K. drafted the manuscript and interpreted the data. All authors read and approved the final manuscript.


* Co-first authors.




Publication History

Received: 20 September 2019

Accepted: 07 January 2020

Article published online:
10 February 2020

© 2020. Thieme. All rights reserved.

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

 

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