Gorlin–Goltz Syndrome with Multidisciplinary Approach of Treatment

Abstract

Gorlin–Goltz syndrome, is an uncommon genetic condition characterized by the presence of multiple odontogenic keratocysts of jaws along with several other abnormal, cutaneous, ophthalmic, and osseous displays. This syndrome is also acknowledged by various names, such as nevoid basal cell carcinoma syndrome, jaw cyst, and bifid rib syndrome. This article illustrates about the clinical, radiological, and histological diagnostic findings and the multidisciplinary approach of treatment given to one such rare case of Gorlin–Goltz syndrome.

Keywords

Gorlin–Goltz syndrome - multiple odontogenic keratocyst syndrome - nevoid basal cell carcinoma syndrome - Gorlin’s syndrome

Publikationsverlauf

Artikel online veröffentlicht:
27. Januar 2020

• References

• 1 Thomas N, Vinod SV, George A, Varghese A. Gorlin-Goltz syndrome: An often missed diagnosis. Ann Maxillofac Surg 2016; 6 (01) 120-124
• 2 Guruprasad Y, Prabhu PR. Gorlin-Goltz syndrome with situs oppositus. Natl J Maxillofac Surg 2010; 1 (01) 58-62
• 3 Sahu S, Sahoo S, Banerjee R, Ghosh S. An enigma of Gorlin-Goltz syndrome: Two cases reported in mother and daughter. J Oral Maxillofac Pathol 2019; 23 (Suppl. 01) 115-121
• 4 Kiwilsza M, Sporniak-Tutak K. Gorlin-Goltz syndrome–a medical condition requiring a multidisciplinary approach. Med Sci Monit 2012; 18 (09) RA145-RA153
• 5 Jawa DS, Sircar K, Somani R, Grover N, Jaidka S, Singh S. Gorlin-Goltz syndrome. J Oral Maxillofac Pathol 2009; 13 (02) 89-92
• 6 Joshi PS, Deshmukh V, Golgire S. Gorlin-Goltz syndrome. Dent Res J (Isfahan) 2012; 9 (01) 100-106
• 7 Witmanowski H, Szychta P, Błochowiak K, Jundziłł A, Czajkowski R. Basal cell nevus syndrome (Gorlin-Goltz syndrome): genetic predisposition, clinical picture and treatment. Postepy Dermatol Alergol 2017; 34 (04) 381-387
• 8 Sebastian J, Nikhilraj. Shakunthala GK, Roshin CN. Diagnostic approach to recurrent multiple odontogenic Cyst—Gorlin–Goltz syndrome. J Indian Acad Oral Med Radiol 2019; 31 (01) 84-87
• 9 Bree AF, Shah MR. BCNS Colloquium Group. Consensus statement from the first international colloquium on basal cell nevus syndrome (BCNS). Am J Med Genet A 2011; 155A [phone]
• 10 Kalogeropoulou C, Zampakis P, Kazantzi S, Kraniotis P, Mastronikolis NS. Gorlin-Goltz syndrome: incidental finding on routine ct scan following car accident. Cases J 2009; 2: 9087
• 11 Charles A. Waldron. Nevoid Basal Cell Carcinoma Syndrome. In: Brad W. Neville, Douglas D. Damm, Carl M. Allen, Jerry E. Bouquot. 1^st ed. Oral and Maxillofacial Pathology. Philadelphia: WB Saunders; 1995: 501-503