Homœopathic Links 2019; 32(04): 216-223
DOI: 10.1055/s-0039-3402080
Original Article
Thieme Medical and Scientific Publishers Private Ltd.

Homeopathic Treatment of Rheumatoid Arthritis: An Open, Observational Trial

Nivedita Kundu
1  Department of Organon of Medicine, Homoeopathic Philosophy, Chronic Diseases and Psychology, National Institute of Homoeopathy, Kolkata, West Bengal, India
,
Mahadeb De
1  Department of Organon of Medicine, Homoeopathic Philosophy, Chronic Diseases and Psychology, National Institute of Homoeopathy, Kolkata, West Bengal, India
,
Subhas Singh
1  Department of Organon of Medicine, Homoeopathic Philosophy, Chronic Diseases and Psychology, National Institute of Homoeopathy, Kolkata, West Bengal, India
,
James Michael
1  Department of Organon of Medicine, Homoeopathic Philosophy, Chronic Diseases and Psychology, National Institute of Homoeopathy, Kolkata, West Bengal, India
,
Arunava Nath
1  Department of Organon of Medicine, Homoeopathic Philosophy, Chronic Diseases and Psychology, National Institute of Homoeopathy, Kolkata, West Bengal, India
,
Nitin Magotra
1  Department of Organon of Medicine, Homoeopathic Philosophy, Chronic Diseases and Psychology, National Institute of Homoeopathy, Kolkata, West Bengal, India
,
Munmun Koley
2  Independent Researcher, Hooghly, West Bengal, India
,
Subhranil Saha
3  Independent Researcher, Howrah, West Bengal, India
› Author Affiliations
Further Information

Publication History

Publication Date:
28 January 2020 (online)

Abstract

Background Rheumatological complaints including rheumatoid arthritis (RA) are frequently encountered conditions in homeopathy practice. On account of progressive destruction and disability of the joints, and troublesome side effects and dissatisfaction with the mainstream therapies, homeopathy remains one of the most sought-after therapies; however, it remained under-researched systematically. Aim of this trial was to evaluate the possible role of homeopathic treatment in RA by determining changes in severity of complaints and quality of life.

Materials and Methods An open observational trial was performed on 50 patients suffering from RA (classified as per 2010 ACR/EULAR criteria) at National Institute of Homoeopathy, Kolkata and were assessed over 4 months of treatment. Disease Activity Score-28 (DAS28) and Rheumatoid Arthritis Disease Activity Index (RADAI) were used as the primary and secondary outcome measures respectively. Individualised medicines were prescribed on the basis of homeopathic principles.

Results Six patients dropped out; 44 completed the trial. Intention-to-treat sample (n = 50) was analysed in the end. There were statistically significant reductions in both DAS28 score (6.8 ± 1.0 vs. 6.1 ± 1.2; mean reduction 0.7, 95% CI: 0.4–0.9, p < 0.001) and RADAI score (6.6 ± 1.8 vs. 5.2 ± 1.9; mean reduction 1.4, 95% CI: 1.0–1.9, p < 0.001) over 4 months of individualised homeopathic treatment.

Conclusion Individualised homeopathic medicines seemed to produce promising treatment effects by reducing DAS28 and RADAI scores significantly over 4 months. Further randomised trials are warranted with enhanced methodological rigor (Trial registration: CTRI/2017/06/008848).

Author Contributions

NK, MD, S. Singh, JM, AN, NM: Concept, literature search, clinical study, data acquisition, data interpretation and preparation of the article; MK and S. Saha: Concept, literature search, design, data interpretation, statistical analysis, preparation of the article. All the authors reviewed and approved the final paper.


Financial Support

We received no funding for the project. The study was conducted as postgraduate thesis of the corresponding author; however, the institution has no role to play in the conduct of the trial or publication of the study findings.


Ethical Approval

The study protocol was approved by the Institutional Ethical Committee (IEC) (Ref. No. 5–023/NIH/PG/Ethical Comm. 2009/Vol. III/ 1952 [A/S]; dated March 27, 2017).


Supplementary Material