J Neurol Surg B
DOI: 10.1055/s-0039-3402012
Original Article
Georg Thieme Verlag KG Stuttgart · New York

En Plaque Meningiomas: A Narrative Review

1  Department of Neurological Surgery, University Hospitals Cleveland Medical Center, Cleveland, Ohio, United States
,
Hana Yokoi
2  Case Western Reserve University School of Medicine, Cleveland, Ohio, United States
,
A. Jessey Chugh
1  Department of Neurological Surgery, University Hospitals Cleveland Medical Center, Cleveland, Ohio, United States
2  Case Western Reserve University School of Medicine, Cleveland, Ohio, United States
,
Carlito Lagman
1  Department of Neurological Surgery, University Hospitals Cleveland Medical Center, Cleveland, Ohio, United States
2  Case Western Reserve University School of Medicine, Cleveland, Ohio, United States
,
Osmond Wu
1  Department of Neurological Surgery, University Hospitals Cleveland Medical Center, Cleveland, Ohio, United States
2  Case Western Reserve University School of Medicine, Cleveland, Ohio, United States
,
Christina Huang Wright
1  Department of Neurological Surgery, University Hospitals Cleveland Medical Center, Cleveland, Ohio, United States
2  Case Western Reserve University School of Medicine, Cleveland, Ohio, United States
,
Abhishek Ray
1  Department of Neurological Surgery, University Hospitals Cleveland Medical Center, Cleveland, Ohio, United States
2  Case Western Reserve University School of Medicine, Cleveland, Ohio, United States
,
Nicholas Bambakidis
1  Department of Neurological Surgery, University Hospitals Cleveland Medical Center, Cleveland, Ohio, United States
2  Case Western Reserve University School of Medicine, Cleveland, Ohio, United States
› Institutsangaben
Weitere Informationen

Publikationsverlauf

05. August 2019

03. November 2019

Publikationsdatum:
23. Dezember 2019 (online)

Abstract

Background En plaque meningiomas are a rare subtype of meningiomas that are frequently encountered in the spheno-orbital region. Characterized by a hyperostotic and dural invasive architecture, these tumors present unique diagnostic and treatment considerations.

Objectives The authors conduct a narrative literature review of clinical reports of en plaque meningiomas to summarize the epidemiology, clinical presentation, diagnostic criteria, and treatment considerations in treating en plaque meningiomas. Additionally, the authors present a case from their own experience to illustrate its complexity and unique features.

Methods A literature search was conducted using the MEDLINE database using the following terminology in various combinations: meningioma, meningeal neoplasms, en plaque, skull base, spheno-orbital, and sphenoid wing. Only literature published in English between 1938 and 2018 was reviewed. All case series were specifically reviewed for sufficient data on treatment outcomes, and all literature was analyzed for reports of misdiagnosed cases.

Conclusion En plaque meningiomas may present with a variety of symptoms according to their location and degree of bone invasion, requiring a careful diagnostic and treatment approach. While early and aggressive surgical resection is generally accepted as the optimal goal of treatment, these lesions require an individualized approach, with further investigation needed regarding the role of new therapies.