Planta Med 2019; 85(18): 1561
DOI: 10.1055/s-0039-3400130
Main Congress Poster
Poster Session 2
© Georg Thieme Verlag KG Stuttgart · New York

St. John´s wort in a large epidemiological study on the use of herbal medicinal products

J Möller
1   Bayer Consumer Health, Innovation & Development, Phytomedicines Supply and Development Center, Steigerwald Arzneimittelwerk GmbH,, Havelstr. 5, 64295 Darmstadt, Germany
,
E Raskopf
2   ClinNovis GmbH,, Genter Str. 7, 50672 Cologne, Germany
3   Institute for Medical Statistics and Computational Biology, University Hospital Cologne,, Kerpener Str. 62, 50937 Cologne, Germany
,
O Greinert
3   Institute for Medical Statistics and Computational Biology, University Hospital Cologne,, Kerpener Str. 62, 50937 Cologne, Germany
,
G Zadoyan
3   Institute for Medical Statistics and Computational Biology, University Hospital Cologne,, Kerpener Str. 62, 50937 Cologne, Germany
,
S Schleicher
3   Institute for Medical Statistics and Computational Biology, University Hospital Cologne,, Kerpener Str. 62, 50937 Cologne, Germany
,
K Shah-Hosseini
3   Institute for Medical Statistics and Computational Biology, University Hospital Cologne,, Kerpener Str. 62, 50937 Cologne, Germany
,
C Kolb
4   Kooperation Phytopharmaka GbR,, Plittersdorfer Str. 218, 53173 Bonn, Germany
,
O Kelber
1   Bayer Consumer Health, Innovation & Development, Phytomedicines Supply and Development Center, Steigerwald Arzneimittelwerk GmbH,, Havelstr. 5, 64295 Darmstadt, Germany
4   Kooperation Phytopharmaka GbR,, Plittersdorfer Str. 218, 53173 Bonn, Germany
,
J Singh
2   ClinNovis GmbH,, Genter Str. 7, 50672 Cologne, Germany
3   Institute for Medical Statistics and Computational Biology, University Hospital Cologne,, Kerpener Str. 62, 50937 Cologne, Germany
,
R Mösges
2   ClinNovis GmbH,, Genter Str. 7, 50672 Cologne, Germany
3   Institute for Medical Statistics and Computational Biology, University Hospital Cologne,, Kerpener Str. 62, 50937 Cologne, Germany
,
K Kraft
4   Kooperation Phytopharmaka GbR,, Plittersdorfer Str. 218, 53173 Bonn, Germany
5   Lehrstuhl für Naturheilkunde, Universitätsmedizin Rostock,, Ernst-Heydemann Str. 6, 18057 Rostock, Germany
,
K Nieber
4   Kooperation Phytopharmaka GbR,, Plittersdorfer Str. 218, 53173 Bonn, Germany
6   Institute of Pharmacy, University of Leipzig,, Brüderstr. 34, 04103 Leipzig, Germany
› Author Affiliations
Further Information

Publication History

Publication Date:
20 December 2019 (online)

Also available at
 

The PhytoVIS study, presumably the largest study worldwide on herbal medicines, is a non-interventional study (NIS) conducted in pharmacies and physician´s offices in Germany with 20,870 patients. It aims to describe the epidemiology, medical needs and perceived effectiveness of the therapy with these products [1]. In this setting, it is of special interest to evaluate the respective data on the St. John´s wort (Hypericum perforatum L.) preparations used in psychic depression to identify potential specific patterns of its therapeutic use.

The total database of 24,056 patient questionnaires was screened for the use of a leading product in this field, Laif 900. Epidemiological data on gender, age and disease state as well as on the use an perception of the herbal product were evaluated.

80 patients taking Laif 900 were identified. The majority of patients was female. The general tolerability of the product was good. In 41% of all patients the perceived effect was very good, and another 43% gave it to be moderate to distinct. Only 4% of patients perceived no effect.

Due to the provenience of the present data from a large non product-specific survey, they augment, despite of the rather small sample size, the available evidence on Hypericum products in moderate depression. The majority of patients gave the effect to be moderate or better with more than a third stating it to be very good. This confirmed the positive rating of its use already described in previous non-interventional and interventional studies [2].

 

  • References

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    PubMed
  • 2 Kresimon J. et al., Gesundh Ökon Qual Manag 2012; 17: 198-206
    PubMed