Planta Med 2019; 85(18): 1392
DOI: 10.1055/s-0039-3399644
Pre-Congress Symposia
Clinical Research
© Georg Thieme Verlag KG Stuttgart · New York

Mistletoe in adjuvant cancer treatment of companion animals

U Biegel
1   Forschungsinstitut für Biologischen Landbau (FiBL), Ackerstrasse 113, 5070 Frick, Switzerland
,
U von Bodungen
2   Praxis 4 Pfoten, Schulweg 5, 2562 Port, Switzerland
,
K Ruess
3   Marigin Center for Veterinary medicine (Veterinary clinic), Firststrasse 31, 8835 Feusisberg, Switzerland
,
M Reif
4   Gesellschaft für klinische Forschung (GFK), Hardenbergstraße 20, 10623 Berlin, Germany
,
Y Knauf
5   Georg-August-Universität-Göttingen (GAUG), Wilhelmsplatz 1, 37073 Göttingen, Germany
,
N Stratmann
6   Tierarztpraxis Dr. Nina Stratmann, Vorhölterstraße 17, 44267 Dortmund, Germany
› Author Affiliations
Further Information

Publication History

Publication Date:
20 December 2019 (online)

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Cancer diseases are frequent in veterinary practice and overall there is a 23% – 45 % risk for dogs to die from cancer. Oral malignant melanoma (OMM) as well as canine mammary tumor (CMT) show high malignancy and adjuvant treatment is needed. The aim of both controlled trials was to explore if viscum album L. extract (VAE) therapy might be a potential treatment of OMM and CTM. In OMM the adjuvant VAE treatment showed a significant longer median survival time (MST) with 236 days compared to the control (radiation only) with 49 days (p = 0,0047). Adjuvant VAE treatment in CMT showed not significant differences in MST compared to the control group (surgery only). A tendency (p= 0,7) of decrease in tumor-related death risk (TRDR) to 25% (HR 0.251, 95% CI 0.056–1.122; p = 0.07) was observed for the treatment group, with stable Quality of life during entire treatment.

 

  • References

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    PubMedSearch in Google Scholar