CC BY 4.0 · European J Pediatr Surg Rep 2019; 07(01): e90-e92
DOI: 10.1055/s-0039-3399565
Case Report
Georg Thieme Verlag KG Stuttgart · New York

Intravesical Oxybutynin for Urgent Bladder Rescue in a Newborn with Posterior Urethral Valves

Ada Molina Caballero
1  Department of Pediatric Surgery, Complejo Hospitalario de Navarra, Pamplona, Spain
,
Alberto Pérez Martínez
1  Department of Pediatric Surgery, Complejo Hospitalario de Navarra, Pamplona, Spain
,
Concepción Goñi Orayen
2  Division of Neonatology, Complejo Hospitalario de Navarra, Pamplona, Spain
,
Gemma Sierra Colomina
2  Division of Neonatology, Complejo Hospitalario de Navarra, Pamplona, Spain
,
Ana Lavilla Oiz
2  Division of Neonatology, Complejo Hospitalario de Navarra, Pamplona, Spain
,
Yolanda Armendariz Cuevas
2  Division of Neonatology, Complejo Hospitalario de Navarra, Pamplona, Spain
› Author Affiliations
Further Information

Publication History

29 April 2019

20 September 2019

Publication Date:
22 November 2019 (online)

  

Abstract

Posterior urethral valves are the most common cause of bladder outlet obstruction in male newborns. Initial catheter drainage alleviates the urethral obstruction before definitive management by valve ablation. Newborns with posterior urethral valves often present with hypercontractile bladders that may inhibit upper tract drainage despite bladder catheterization. Anticholinergic agents are commonly used to treat detrusor hyperactivity, with oxybutynin being the most commonly used. We report the first case of a newborn with posterior urethral valves and ureterovesical junction obstruction caused by detrusor hypertrophy who underwent urgent intravesical instillation of oxybutynin at high doses in an attempt to avoid a diversion procedure.