CC BY-NC-ND 4.0 · Indian J Plast Surg 2011; 44(03): 474-477
DOI: 10.1055/s-0039-1699520
Association of Plastic Surgeons of India

Collagen sheet dressings for cutaneous lesions of toxic epidermal necrolysis

S. Bhattacharya
Department of Plastic Surgery, Sahara Hospital and Ajanta Hospital, Lucknow, Uttar Pradesh, India
H. N. Tripathi
1  Department of Internal Medicine, Lucknow, Uttar Pradesh, India
V. Gupta
2  Department of Dermatology and Sahara Hospital, Lucknow, Uttar Pradesh, India
Bharti Nigam
3  Department of Ophthalmology, Sahara Hospital, Lucknow, Uttar Pradesh, India
A. Khanna
4  Department of Surgery, Ajanta Hospital, Lucknow, Uttar Pradesh, India
› Author Affiliations
Further Information

Publication History

Publication Date:
31 December 2019 (online)


Toxic epidermal necrolysis (TEN) is associated with a significant mortality of 30–50% and long-term sequelae. Treatment includes early admission to a burn unit, where management with precise fluid, electrolyte, protein, and energy supplementation, moderate mechanical ventilation, and expert wound care can be provided. Specific treatment with immunosuppressive drugs or immunoglobulins did not show an improved outcome in most studies and remains controversial. We have treated the cutaneous lesions of seven patients of TEN with collagen sheet dressings and have found a significant reduction in morbidity. The sheets are a one-time dressing, easy to apply and they reduce fluid loss, prevent infection, reduce pain, avoid repeated dressings and gradually peal off as the underlying lesions heal.


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