CC BY-NC-ND 4.0 · Indian J Plast Surg 2011; 44(02): 298-307
DOI: 10.1055/s-0039-1699507
Review Article
Association of Plastic Surgeons of India

Complex regional pain syndrome

Sandeep J Sebastin
Department of Hand and Reconstructive Microsurgery, National University Health System, Singapore
› Author Affiliations
Further Information

Publication History

Publication Date:
31 December 2019 (online)


Complex regional pain syndrome (CRPS) previously known as reflex sympathetic dystrophy is a chronic neurological disorder involving the limbs characterized by disabling pain, swelling, vasomotor instability, sudomotor abnormality, and impairment of motor function. CRPS is not uncommon after hand surgery and may complicate post-operative care. There is no specific diagnostic test for CRPS and the diagnosis is based on history, clinical examination, and supportive laboratory findings. Recent modifications to diagnostic criteria have enabled clinicians to diagnose this disease more consistently. This review gives a synopsis of CRPS and discusses the diagnosis, pathophysiology, and treatment options based on the limited evidence in the literature.


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