CC BY-NC-ND 4.0 · Eur J Dent 2013; 07(01): 145-151
DOI: 10.1055/s-0039-1699010
Original Article
Dental Investigation Society

Nanotechnology and dentistry

Sule Tugba Ozak
1   Department of Prosthodontics, Faculty of Dentistry, Ankara University
Pelin Ozkan
1   Department of Prosthodontics, Faculty of Dentistry, Ankara University
› Author Affiliations
Further Information

Publication History

Publication Date:
30 September 2019 (online)


Nanotechnology deals with the physical, chemical, and biological properties of structures and their components at nanoscale dimensions. Nanotechnology is based on the concept of creating functional structures by controlling atoms and molecules on a one-by-one basis. The use of this technology will allow many developments in the health sciences as well as in materials science, biotechnology, electronic and computer technology, aviation, and space exploration. With developments in materials science and biotechnology, nanotechnology is especially anticipated to provide advances in dentistry and innovations in oral health-related diagnostic and therapeutic methods. (Eur J Dent 2013;7:145-151)

  • References

  • 1 Saravana KR, Vijayalakshmi R. Nanotechnology in dentistry. Ind J Dent Res 2006;17:62-65.
  • 2 Schleyer TL. Nanodentistry: Fact or fiction? J Am Dent Assoc 2000;131:1567-1568.
  • 3 Erkoç Ş. Nanobilim ve Nanoteknoloji. 1.Baskı, Ankara: ODTÜ Yayıncılık; 2007, p.1-10
  • 4 Gumusderelioglu M, Mavis B, Karakecli A, Kahraman AS, Cakmak S, Tigli S, Demirtas TT, Aday S. Doku mühendisliğinde nanoteknoloji. Bilim ve Teknik 2007;479: Ek.
  • 5 Kong LX, Peng Z, Li SD, Bartold M. Nanotechnology and its role in the management of periodontal diseases. Periodontol 2000 2006;40:184-196.
  • 6 Mansoori GA. Advances in atomic and molecular nanotechnology. Principles of Nanotechnology. 1st ed. Singapore: World Scientific Publishing Co. Ptc. Ltd; 2005, p.1-10.
  • 7 Rieth M. Nano-Engineering – Studies and Conclusions. Nano-Engineering in science and technology. 1st ed. Singapore: World Scientific Publishing Co. Ptc. Ltd; 2003, p.91-103.
  • 8 Ozbay E. İşe yarar nanoteknoloji. Seminer, Bilkent Üniv. Nanoteknoloji Araştırma Merkezi, Ankara, Turkey; 2006.
  • 9 Poole PC Jr, Owens FJ. Introduction to Nanotechnology. New Jersey: John Wiley & Sons Inc; 2003, p. 1-7.
  • 10 Duke ES. Has dentistry moved into the nanotechnology era? Compend Contin Educ Dent 2003;24:380-382.
  • 11 Freitas JR RA. Nanodentistry. J Am Dent Assoc 2000;131:1559-1565.
  • 12 Freitas JR RA. Nanomedicine: Basic Capabilities. Volume 1. Landes Biosciences. Retrieved online January 3, 2008 from:
  • 13 Freitas JR RA. What is nanomedicine? Nanomedicine 2005;1:2-9.
  • 14 Freitas JR RA. Nanotechnology, nanomedicine and nanosurgery. Int J Surg 2005;3:243-246.
  • 15 Caruthers SD, Wickline SA, Lanza GM. Nanotechnological applications in medicine. Current Opin Biotechnol 2007;18:26-30.
  • 16 Stephen CB. Dental Biomaterials: Where Are We and Where Are We Going? J Dent Educ 2005;69:571-578.
  • 17 Roberson MT, Heymann OH, Swift JR EJ. Biomaterials. Sturdevant’s Art and Science of Operative Dentistry. 5th ed. Mosby Co; 2006, p.137-139.
  • 18 Ashammakhi N, Ndreu A, Yang Y, Ylikauppila H, Nikkola L, Hasırcı V. Tissue engineering: A new take-off using nanofiber- based scaffolds. J Craniofac Surg 2007;18:3-17.
  • 19 Strietzel FP, Reichart PA, Graf HL. Lateral alveolar ridge augmentation using a synthetic nano-crystalline hydroxiapatite bone substitution material (Ostim®). Clin Oral Impl Res 2007;18:743-751.
  • 20 Wagner V, Dullart A, Bock AK, Zweck A. The emerging nanomedicine landscape. Nature Biotechnology 2006; 24: 2–9. Retrieved online February 2, 2008 from:
  • 21 Kasaj A, Willershausen B, Reichert C, Röhrig B, Smeets R, Schmidt M. Ability of nanocrystalline hydroxyapatite paste to promote human periodontal ligament cell proliferation. J Oral Sci 2008;50:279-285.
  • 22 Tetè S, Mastrangelo F, Traini T, Vinci R, Sammartino G, Marenzi G, Gherlone E. A macro- and nanostructure evaluation of a novel dental implant. Implant Dent 2008;17:309- 320.
  • 23 Braceras I, De Maeztu MA, Alava JI, Gay-Escoda C. In vivo low-density bone apposition on different implant surface materials. Int J Oral Maxillofac Surg 2009;38:274-278.
  • 24 Ellingsen JE, Thomsen P, Lyngstadaas P. Advances in dental implant materials and tissue regeneration. Periodontol 2000 2006;41:136-156.
  • 25 Suh JY, Jeung OC, Choi BJ, Park JW Effects of a novel calcium titanate coating on the osseointegration of blasted endosseous implants in rabbit tibiae. Clin Oral Impl Res 2007;18:362-369.
  • 26 Meirelles L, Currie F, Jacobsson M, Albrektsson T, Wennerberg A. The effect of chemical and nanotopographical modifications on the early stages of osseointegration. Int J Oral Maxillofac Impl 2008;23:641-647.
  • 27 Chiang CY, Chiou SH, Yang WE, Hsu ML, Yung MC, Tsai ML, Chen LK, Huang HH. Formation of TiO(2) nano-network on titanium surface increases the human cell growth. Dent Mater 2009;25:1022-1029.
  • 28 Park JW, Kim HK, Kim YJ, An CH, Hanawa T. Enhanced osteoconductivity of micro-structured titanium implants (XiVE S CELLplus) by addition of surface calcium chemistry: a histomorphometric study in the rabbit femur. Clin Oral Implants Res 2009;20:684-690.
  • 29 Türkün LŞ, Uzer Çelik E. Antibakteriyal adeziv ile uygulanan kompomer ve nanofil kompozit restorasyonların bir yıllık klinik performansı. Gazi Üniv Diş Hek Fak Derg 2007;24:1-8.
  • 30 Papadogiannis DY, Lakes RS, Papadogiannis Y, Palaghias G, Helvatjoglu-Antoinades M. The effect of temperature on viscoelastic properties of nano-hybrid composites. Dent Mater 2008;24:257-266.
  • 31 Jung M, Sehr K, Klimek J. Surface texture of four nanofilled and one hybrid composite after finishing. Oper Dent 2007;32:45-52.
  • 32 Ernst CP, Brandenbusch M, Meyer G, Canbek K, Gottschalk F, Willershausen B. Two- year clinical performance of a nanofiller vs a fine-particle hybrid resin composite. Clin Oral Invest 2006;10:119-125.
  • 33 Mitra SB, Wu D, Holmes BN. An application of nanotechnology in advanced dental materials. J Am Dent Assoc 2003;134:1382-1390.
  • 34 Yesil ZD, Alapatı S, Johnston W, Seghi RR. Evaluation of the wear resistance of new nanocomposite resin restorative materials. J Prosthet Dent 2008;99:435-443.
  • 35 Joniot S, Salomon JP, Dejou J, Grégoire G. Use of two surface analyzers to evaluate the surface roughness of four esthetic restorative materials after polishing. Oper Dent 2006;31:39-46.
  • 36 Davis N. A nanotechnology composite. Compend Contin Educ Dent 2003;24:662-670.
  • 37 Curtis AR, Palin WM, Fleming GJP, Shortall ACC, Marquis PM. The mechanical properties of nanofilled resin-based composites: The impact of dry and wet cyclic pre-loading on bi-axial flexure strength. Dent Mater 2009;25:188-197.
  • 38 Pinnavaia TJ, Beall GW. Polymer-Clay Nanocomposites. West Sussex, England: John Wiley & Sons Ltd; 2000, p.1-8.
  • 39 Watanabe H, Khera SC, Vargas MA, Qian F. Fracture toughness comparison of six resin composites. Dent Mater 2008;24:418-425.
  • 40 Schirrmeister JF, Huber K, Hellwig E, Hahn P. Two-year evaluation of a new nano-ceramic restorative material. Clin Oral Invest 2006;10:181-186.
  • 41 Suzuki S. In vitro wear of nano-composite denture teeth. J Prosthodont 2004;13:238-243.
  • 42 Ghazal M, Hedderich J, Kern M. Wear of fekdspathic ceramic, nanofilled composite resin and acrylic resin artificial teeth when opposed to different antogonists. Eur J Oral Sci 2008;116:585-592.
  • 43 Ghazal M, Albashaireh ZS, Kern M. Wear resistance of nanofilled composite and feldspathic ceramic artificial teeth. J Prosthet Dent 2008;100:441-448.
  • 44 Loyaga-Rendon PG, Takahashi H, Hayakawa I, Iwasaki N. Compositional characteristics and hardness of acrylic and composite resin artificial teeth. J Prosthet Dent 2007;98:141-149.
  • 45 Imamura S, Takahashi H, Hayakawa I, Loyaga-Rendon PG, Minakuchi S. Effect of filler type and polishing on the discoloration of composite resin artificial teeth. Dent Mater J 2008;27:802-808.
  • 46 Lee SY, Kwon, HK, Kim BI. Effect of dentinal tubule occlusion by dentifrice containing nano-carbonate apatite. J Oral Rehabil 2008;35:847-853.
  • 47 Nakashima S, Yoshie M, Sano H, Bahar A. Effect of a test dentifrice containing nano-sized calcium carbonate on remineralization of enamel lesions in vitro. J Oral Sci 2009;51:69-77.
  • 48 Hernández-Sierra JF, Ruiz F, Pena DC, Martínez-Gutiérrez F, Martínez AE, Guillén Ade J, Tapia-Pérez H, Castañón GM. The antimicrobial sensitivity of Streptococcus mutans to nanoparticles of silver, zinc oxide, and gold. Nanomedicine 2008;4:237-240.
  • 49 Mupparapu, M. New nanophosphor scintillators for solid- state digital dental imagers. Dentomaxillofac Radiol 2006;35:475-476.
  • 50 Troulis MJ, Ward BB, Zuniga JA. Emerging Technologies: Findings of the 2005 AAOMS Research Summit. J Oral Maxillofac Surg 2005;63:1436-1442.