Intracardiac Metastasis from a Large Cell Neuroendocrine Lung Carcinoma

Abstract

Primary malignant tumors of the heart are rare; the biggest group is sarcomas. Cardiac metastases make up the biggest group of secondary cardiac tumors. We present a rare case of cardiac metastasis (3.1 × 3.2 × 2.8 cm) localized in the right atrium, originating from a large cell neuroendocrine lung carcinoma, with close contact to the tricuspid valve and inferior cava vein.

Keywords

cardiac tumor - cardiovascular - surgery - metastases - lung cancer - heart - tricuspid valve

• References

• 1 Lam KY, Dickens P, Chan AC. Tumors of the heart. A 20-year experience with a review of 12,485 consecutive autopsies. Arch Pathol Lab Med 1993; 117 (10) 1027-1031
• 2 Buja LM. The multifaceted manifestations of cardiac tumors. Tex Heart Inst J 2012; 39 (01) 84-85
• 3 Wenger NK. Pericardial disease in the elderly. Cardiovasc Clin 1992; 22 (02) 97-103
• 4 McAllister HA, Fenoglio JJ. Tumors of the Cardiovascular System. Atlas of Tumor Pathology, Series 2. Washington DC: Armed Forces Institute of Pathology; 1978
• 5 Iyoda A, Hiroshima K, Toyozaki T, Haga Y, Fujisawa T, Ohwada H. Clinical characterization of pulmonary large cell neuroendocrine carcinoma and large cell carcinoma with neuroendocrine morphology. Cancer 2001; 91 (11) 1992-2000
• 6 Takei H, Asamura H, Maeshima A. , et al. Large cell neuroendocrine carcinoma of the lung: a clinicopathologic study of eighty-seven cases. J Thorac Cardiovasc Surg 2002; 124 (02) 285-292
• 7 Bussani R, De-Giorgio F, Abbate A, Silvestri F. Cardiac metastases. J Clin Pathol 2007; 60 (01) 27-34
• 8 Quaedvlieg PF, Visser O, Lamers CB, Janssen-Heijen ML, Taal BG. Epidemiology and survival in patients with carcinoid disease in The Netherlands. An epidemiological study with 2391 patients. Ann Oncol 2001; 12 (09) 1295-1300