CC BY-NC-ND 4.0 · Joints 2019; 07(02): 056-063
DOI: 10.1055/s-0039-1697608
Review Article
Georg Thieme Verlag KG Stuttgart · New York

Hip Spacers in Two-Stage Revision for Periprosthetic Joint Infection: A Review of Literature

1  Scuola di Specializzazione in Ortopedia e Traumatologia, Università degli Studi di Torino, Torino, Italy
,
Matteo Bruzzone
2  SC Ortopedia e Traumatologia, AO Ospedale Mauriziano Umberto I, Torino, Italy
,
Umberto Cottino
2  SC Ortopedia e Traumatologia, AO Ospedale Mauriziano Umberto I, Torino, Italy
,
Emilio Enrietti
1  Scuola di Specializzazione in Ortopedia e Traumatologia, Università degli Studi di Torino, Torino, Italy
,
Roberto Rossi
2  SC Ortopedia e Traumatologia, AO Ospedale Mauriziano Umberto I, Torino, Italy
› Author Affiliations
Further Information

Publication History

18 March 2018

06 August 2019

Publication Date:
11 October 2019 (online)

  

Abstract

Infection after total hip arthroplasty (THA) is a devastating complication with significant consequences for patients. In literature, single and two-stage revision, irrigation and debridement, Girdlestone resection arthroplasty, and arthrodesis and amputation are reported as possible treatments. Recently, two-stage revision has become popular as the gold standard treatment for chronic hip joint infections after THA. In this review, we evaluate the current literature about microbiology of periprosthetic joint infections and the use of antibiotic-loaded cement spacers. We aim to give an overview about indications, clinical results, and mechanical complications for spacers implantation, evaluating also selection criteria, pharmacokinetic properties, and systemic safety of the most frequently used antibiotics.