Confirmation of Brain Death with Positron Emission TomographyFunding None declared.
19 May 2019
25 July 2019
06 September 2019 (online)
After recent advances regarding organ transplantation, accurate and timely diagnosis of brain death has gained importance. In the diagnosis of brain death, in addition to clinical findings, various ancillary tests are very crucial. In this study, the scintigraphic imaging of the brain death of an 8-year-old girl with both Tc-99m diethylenetriaminepentaacetic and 18F-fluorodeoxyglucose (FDG) has been presented. This case study shows that 18F-FDG positron emission tomography-computed tomography imaging can be a useful technique in evaluating brain death in patients.
All authors contributed equally to this work, read, and approved the final manuscript.
- 1 Oderberg DS. Death, unity, and the brain. Theor Med Bioeth 2019; 40 (05) 359-379
- 2 Wilson K, Gordon L, Selby Sr JB. The diagnosis of brain death with Tc-99m HMPAO. Clin Nucl Med 1993; 18 (05) 428-434
- 3 Sinha P, Conrad GR. Scintigraphic confirmation of brain death. Semin Nucl Med 2012; 42 (01) 27-32
- 4 Kirschen MP, Francoeur C, Murphy M. , et al. Epidemiology of brain death in pediatric intensive care units in the United States. JAMA Pediatr 2019; 173 (05) 469-476
- 5 Li Y, Liu S, Xun F, Liu Z, Huang X. Use of transcranial doppler ultrasound for diagnosis of brain death in patients with severe cerebral injury. Med Sci Monit 2016; 22: 1910-1915
- 6 Shewmon DA. False-positive diagnosis of brain death following the pediatric guidelines: case report and discussion. J Child Neurol 2017; 32 (14) 1104-1117
- 7 Spieth ME, Ansari AN, Kawada TK, Kimura RL, Siegel ME. Direct comparison of Tc-99m DTPA and Tc-99m HMPAO for evaluating brain death. Clin Nucl Med 1994; 19 (10) 867-872
- 8 Meyer MA. Evaluating brain death with positron emission tomography: case report on dynamic imaging of 18F-fluorodeoxyglucose activity after intravenous bolus injection. J Neuroimaging 1996; 6 (02) 117-119