CC BY 4.0 · Rev Bras Ginecol Obstet 2019; 41(09): 575-578
DOI: 10.1055/s-0039-1695020
Case Report
Thieme Revinter Publicações Ltda Rio de Janeiro, Brazil

Vulvar Tuberculosis—A Rare Manifestation of the Disease

Tuberculose vulvar – Uma manifestação rara da doença
1   Hospital José Joaquim Fernandes, Beja, Portugal
,
Inês Gonçalves
2   Hospital CUF Almada, Almada, Portugal
,
Luísa Guerreiro
1   Hospital José Joaquim Fernandes, Beja, Portugal
,
Maria Janeiro
1   Hospital José Joaquim Fernandes, Beja, Portugal
› Author Affiliations
Further Information

Publication History

09 January 2019

13 June 2019

Publication Date:
03 September 2019 (online)

Abstract

Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis. According to data from the World Health Organization, this disease remains one of the leading causes of death worldwide. Although it most commonly affects the lungs, tuberculosis can compromise any organ. The present study reports a rare case of vulvar tuberculosis in a postmenopausal woman with a history of asymptomatic pulmonary and pleural tuberculosis, with no prior documented contact with the bacillus. Diagnosis was based on vulvar lesion biopsies, with histological findings suggestive of infection and isolation of M. tuberculosis by microbiological culture and polymerase chain reaction (PCR) essays. The lesions reverted to normal after tuberculostatic therapy.

Resumo

A tuberculose é uma doença infeciosa causada pelo Mycobacterium tuberculosis. De acordo com dados da Organização Mundial de Saúde, esta doença mantém-se entre as principais causas de morte no mundo. Embora afete mais frequentemente os pulmões, a tuberculose pode comprometer qualquer órgão. O presente artigo relata um caso raro de tuberculose vulvar numa mulher na pós-menopausa, com antecedentes de tuberculose pleural e pulmonar assintomática, sem contato documentado com o bacilo. O diagnóstico foi feito com base na biópsia da lesão vulvar, com achados histológicos sugestivos da infeção e isolamento do M. tuberculosis por meios de cultura e pela técnica da reação em cadeia da polimerase (PCR). Após terapêutica tuberculostática, as lesões reverteram.

 
  • References

  • 1 Lyon S, Rossman M. Pulmonary tuberculosis. Microbiol Spectr 2017; 5 (01) DOI: 10.1128/microbiolspec.TNMI7-0032-2016.
  • 2 Zajaczkowski T. Genitourinary tuberculosis: historical and basic science review: past and present. Cent European J Urol 2012; 65 (04) 182-187 . Doi: 10.5173/ceju.2012.04.art1
  • 3 Maiti K, Mishra S, Bera M, Pal D, Maiti M, Mondal PP. Primary vulvar tuberculosis presenting as multiple vulvar ulcers: a rare case report. UroToday Int J. 2013; 6 (03) 39 . Doi: 10.3834/uij.1944-5784.2013.06.13
  • 4 Mallya V, Yadav YK, Gupta K. Vulval tuberculosis masquerading as vulval carcinoma. J Postgrad Med 2012; 58 (04) 307-308 . Doi: 10.4103/0022-3859.105463
  • 5 Ferreira C, Pinto E, Rocha I, Osório M, Felgueira E. Tuberculose genital como causa de infertilidade. Acta Obstet Ginecol Port 2013; 7 (03) 219-222
  • 6 Arakeri SU, Sinkar P. An unusual gross appearance of vulval tuberculosis masquerading as tumor. Case Rep Obstet Gynecol 2014; 2014: 815401 . Doi: 10.1155/2014/815401
  • 7 Tiwari P, Pal DK, Moulik D, Choudhury MK. Hypertrophic tuberculosis of vulva--a rare presentation of tuberculosis. Indian J Tuberc 2010; 57 (02) 95-97
  • 8 World Health Organization. Global Tuberculosis Report. Geneva: WHO; 2018 http://www.who.int/iris/handle/10665/274453 . Accessed December 10, 2018
  • 9 Manoj K, Soma M, Ajay L, Ashish A, Rakesh S, Paliwal RV. Tubercular sinus of labia majora: rare case report. Infect Dis Obstet Gynecol 2008; 2008: 817515 . Doi: 10.1155/2008/817515
  • 10 Nanjappa V, Suchismitha R, Devaraj HS, Shah MB, Anan A, Rahim SN. Vulval tuberculosis - an unusual presentation of disseminated tuberculosis. J Assoc Physicians India 2012; 60: 49-52
  • 11 Mondal SK. Histopathologic analysis of female genital tuberculosis: a fifteen-year retrospective study of 110 cases in eastern India. Turk Patoloji Derg 2013; 29 (01) 41-45 . Doi: 10.5146/tjpath.2013.01146