Int J Angiol
DOI: 10.1055/s-0039-1694780
Case Report
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Successful Treatment of Recurrent Thrombosis Associated with Malignancy with Apixaban and Follow-up for 1 Year

Timothy Boey
1  Anglo-Chinese Junior College, Singapore
Ashita Ashish Sule
2  Raffles Girl's School (Secondary), Singapore
Ashish Anil Sule
3  Department of General Medicine, Vascular Medicine and Hypertension, Tan Tock Seng Hospital, Singapore
› Author Affiliations
Further Information

Publication History

Publication Date:
07 August 2019 (online)


This case report aims to highlight a successful example of using novel oral anticoagulants (NOACs), such as apixaban, to prevent recurrent venous thromboembolism (VTE) in patients with solid-organ malignancy, as an alternative to low-molecular weight heparin (LMWH). Discussed is the case of a 67-year-old woman diagnosed with recurrent thrombosis in the upper-right limb and malignancy of right breast with metastasis to the axillary lymph nodes. Over a follow-up period of more than 1 year, there was no recurrence of VTE and D-dimer decreased, illuminating the possibility of apixaban as an alternative form of treatment for recurrent VTE in patients with malignancy. This appears to be one of the first case reports in Singapore.