Portal Hypertensive Biliopathy in Adult Patients: Findings and Interventional Radiologic Treatment—A Single-Center Experience

Alberta Cappelli; Francesco Modestino; Cristina Mosconi; Caterina De Benedittis; Antonio Bruno; Dimitris Papadopoulos; Giovanni Vitale; Alessandro Cucchetti; Sonia Berardi; Maria Cristina Morelli; Rita Golfieri

doi:10.1055/s-0039-1693514

Seminars in Liver Disease, Inhaltsverzeichnis

Semin Liver Dis 2019; 39(04): 502-512
DOI: 10.1055/s-0039-1693514

Review Article

Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Portal Hypertensive Biliopathy in Adult Patients: Findings and Interventional Radiologic Treatment—A Single-Center Experience

Alberta Cappelli

¹Department of Diagnostic Medicine and Prevention, Radiology Unit, S. Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy

,

Francesco Modestino

¹Department of Diagnostic Medicine and Prevention, Radiology Unit, S. Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy

,

Cristina Mosconi

¹Department of Diagnostic Medicine and Prevention, Radiology Unit, S. Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy

,

Caterina De Benedittis

¹Department of Diagnostic Medicine and Prevention, Radiology Unit, S. Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy

,

Antonio Bruno

¹Department of Diagnostic Medicine and Prevention, Radiology Unit, S. Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy

,

Dimitris Papadopoulos

²Radiology Unit, “C. A. Pizzardi” Maggiore Hospital, Bologna, Italy

,

Giovanni Vitale

³Department of Organ Failure and Transplantation, Internal Medicine, S. Orsola-Malpighi Hospital, Alma Mater Studiorum, University of Bologna, Bologna, Italy

,

Alessandro Cucchetti

⁴General and Oncology Surgery, Morgagni-Pierantoni Hospital, Forli, Italy

⁵Department of Medical & Surgical Sciences, DIMEC, Alma Mater Studiorum, University of Bologna, Bologna, Italy

,

Sonia Berardi

³Department of Organ Failure and Transplantation, Internal Medicine, S. Orsola-Malpighi Hospital, Alma Mater Studiorum, University of Bologna, Bologna, Italy

,

Maria Cristina Morelli

³Department of Organ Failure and Transplantation, Internal Medicine, S. Orsola-Malpighi Hospital, Alma Mater Studiorum, University of Bologna, Bologna, Italy

,

Rita Golfieri

¹Department of Diagnostic Medicine and Prevention, Radiology Unit, S. Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy

› Institutsangaben

Abstract

The aim of this study was to evaluate the morphologic appearance, the clinical scenario, and the outcomes of patients with portal hypertensive biliopathy (PHB), particularly in the symptomatic subgroup treated with interventional radiology (IR) procedures. The outcome of 20 patients with PHB were retrospectively reviewed over a 5-year period. In all cases, the extrahepatic portal vein occlusion (EHPVO) and the compensatory cavernomatosis was the cause of PHB. Eight out of 20 patients had severe symptoms (jaundice and bleeding). Five out of these eight patients were successfully treated with IR procedures. PHB is a rare but serious complication of PH from EHPVO. IR treatments are highly effective in controlling symptoms. Moreover, IR procedures, as drainage and transjugular intrahepatic portosystemic shunt placement, are the first-line treatment in cases of life-threatening bleeding from ruptures of the varices.

Keywords

portal biliopathy - portal vein obstruction - portal cavernoma - biliary obstruction

Volltext

Referenzen

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