Abstract
Insulin is a naturally occurring hormone secreted by the pancreas. Insulin is required
by the body cellsto remove and use glucose from the blood. The insulin and its various
analogues are essential in management of type 1 diabetes mellitus. This study has
been done to analyze how variation in various storage conditions and climatic changes
causes change in therapeutic efficacy. Storage condition affects the stability of
insulin as observed in a study in which insulin stored at temperature between 32 and
37°C showed 14 to 18% decrease in its potency and could not cause a significant decrease
in blood sugar level when compared with those receiving insulin stored at 5°C. This
work was done with the aim of finding the effect of climatic changes and storage condition
on efficacy of insulin.
Keywords
insulin - climatic changes - therapeutic efficacy
