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Comparing the Complication Rate of Different TPLO Fixation Systems in Dogs over > 45.4 Kg (100 LBS)
07 August 2019 (online)
Introduction: Cranial cruciate ligament rupture is the most common canine stifle condition. Large dog TPLO have high complication rates. No studies have compared the complication rates of different TPLO fixation systems in large dogs. Our goal was to compare the complication rate of three TPLO fixation systems in dogs > 45.4 kg. Our null hypothesis was the type of TPLO fixation system was not associated with complications.
Materials and Methods: The medical records of dogs treated with TPLO were reviewed (> 6-week follow-up). A random effects logistic regression model was used to evaluate the association between the type of TPLO fixation system and complications.
Results: The study included 342 TPLO surgeries. The fixation systems included 3.5 mm broad Unity Cruciate Plate (UCP) (8P) (78.4%), 3.5 mm broad UPC (14.9%) with String of Pearls plate (8AP), and 3.5 mm standard UPC (6P) (6.7%). There were 214 locking and 128 nonlocking systems. The statistical model controlled the confounding effects of weight differences between fixation systems. The fixation system was predictive of complications. The 8P had the lowest odds ratio [OR] for complication among the three fixation systems. The 8AP had higher odds of complications than the 8P. Locking fixation eliminated the association between weight and complication rate.
Discussion/Conclusion: The null hypothesis was rejected. Among the fixation systems, 8AP had the highest OR for complication. Contributing factors may include excessive soft tissue dissection, prolonged surgical, and anesthesia time. Locking fixation of TPLO with 8P may be considered in large dogs to reduce complications.
Acknowledgment: No proprietary interest or funding was provided.