Semin Liver Dis
DOI: 10.1055/s-0039-1687853
Review Article
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Magnetic Resonance Imaging in Primary Sclerosing Cholangitis—Current State and Future Directions

Roman Zenouzi
1  1st Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
,
Christopher L. Welle
2  Department of Radiology Mayo Clinic, Rochester, Minnesota
,
Sudhakar K. Venkatesh
2  Department of Radiology Mayo Clinic, Rochester, Minnesota
,
Christoph Schramm
1  1st Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
3  Martin Zeitz Center for Rare Diseases, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
,
John E. Eaton
4  Division of Gastroenterology and Hepatology Mayo Clinic, Rochester, Minnesota
› Author Affiliations
Further Information

Publication History

Publication Date:
30 April 2019 (eFirst)

Abstract

Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease characterized by biliary inflammation and fibrosis leading to bile duct strictures, cirrhosis, and carries an increased risk of hepatobiliary malignancies. Magnetic resonance imaging (MRI) with magnetic resonance cholangiopancreatography (MRCP) is the imaging modality of choice in PSC. As an evolving technology, MRI has other potential applications in the care and study of those patients with PSC. In this review, the authors aim to provide a technical overview on MRI/MRCP and related technologies, summarize its contemporary use in PSC, and discuss its evolving role to predict outcomes and look ahead toward emerging MRI technologies relevant to PSC.