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Thromb Haemost 1979; 41(01): 3-23
DOI: 10.1055/s-0039-1687181
Dedication
Schattauer GmbH

A Tribute to Kenneth M. Brinkhous, M. D.

Sol SHERRY
1   Professor and Chairman, Department of Medicine. Temple University School of Medicine, Health Sciences Center, Philadelphia, U.S.A.
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Publication History

Publication Date:
15 April 2019 (online)

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  • Bibliography of Kenneth M. Brinkhous

    • A. Research Publications

    • 1 Smith H.P., Warner E.D., Brinkhous K.M.. 1934; Lung extract and blood clotting. Am. J. Physiol. 107: 63.
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    • 2 Warner E.D., Brinkhous K.M., Smith H.P.. 1936; A quantitative study on blood clotting: prothrombin fluctuations under experimental conditions. Am. J. Physiol. 114: 667.
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    • 3 Hawkins W.B., Brinkhous K.M.. 1936; Prothrombin deficiency the cause of bleeding in bile fistula dogs. J. Exp. Med. 63: 795.
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    • 4 Brinkhous K.M., Smith H.P., Warner E.D.. 1937; Plasma prothrombin level in normal infancy and in hemorrhagic disease of the newborn. Am. J. Med. Sci. 193: 475.
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    • 5 Smith H.P., Warner E.D., Brinkhous K.M.. 1937; Prothrombin deficiency and the bleeding tendency in liver injury (chloroform intoxication). J. Exp. Med. 66: 801.
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    • 6 Warner E.D., Brinkhous K.M., Smith H.P.. 1938; Bleeding tendency of obstructive jaundice: prothrombin deficiency and dietary factors. Proc. Soc. Exp. Biol. Med. 37: 628.
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    • 7 Seegers W.H., Smith H.P., Warner E.D., Brinkhous K.M.. 1938; The purification of prothrombin. J. Biol. Chem. 123: 751.
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    • 8 Smith H.P., Warner E.D., Brinkhous K.M., Seegers W.H.. 1938; Bleeding tendency and prothrombin deficiency in biliary fistula dogs: effect of feeding bile and vitamin K. J. Exp. Med. 67: 911.
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    • 9 Brinkhous K.M., Smith H.P., Warner E.D.. 1938; Prothrombin deficiency and the bleeding tendency in obstructive jaundice and in biliary fistula. (Effect of feeding bile and alfalfa - Vitamin K). Am. J. Med. Sci. 196: 50.
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    • 10 Seegers W.H., Brinkhous K.M., Smith H.P., Warner E.D.. 1938; The purification of thrombin. J. Biol. Chem. 126: 91.
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    • 11 Warner E.D., Brinkhous K.M., Smith H.P.. 1939; Plasma prothrombin levels in various vertebrates. Am. J. Physiol. 125: 296.
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    • 12 Warner E.D., Brinknous K.M., Smith H.P.. 1939; The prothrombin conversion rate in various species. Proc. Soc. Exp. Biol. Med. 40: 197.
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    • 13 Brinkhous K.M., Smith H.P., Warner E.D., Seegers W. H.. 1939; The inhibition of blood clotting: an unidentified substance which acts in conjunction with heparin to prevent the conversion of prothrombin into thrombin. Am. J. Physiol. 125: 683.
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    • 14 Scanlon G.H., Brinkhous K.M., Warner E.D., Smith H.P., Flynn J.E.. 1939; Plasma prothrombin and the bleeding tendency, with special reference to jaundiced patients and vitamin K therapy. J.A.M.A. 112: 1898.
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    • 15 Warner E.D., Brinkhous K.M., Seegers W.H., Smith H.P.. 1939; Further experience with the use of thrombin as a hemostatic agent. Proc. Soc. Exp. Biol. Med. 41: 655.
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    • 16 Knowlton G.C., Hines H.M., Brinkhous K.M.. 1939; Effect of wheat germ oil upon E-deficient muscular dystrophy. Proc. Soc. Exp. Biol. Med. 41: 453.
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    • 17 Brinkhous K.M.. 1939; A study of the clotting defect in hemophilia: the delayed formation of thrombin. Am. J. Med. Sci. 198: 509.
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    • 18 Knowlton G.D., Hines H.M., Brinkhous K.M.. 1939; Cure and prevention of vitamin E-deficient muscular dystrophy with synthetic A-to-copherol acetate. Proc. Soc. Exp. Biol. Med. 42: 804.
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    • 19 Brinkhous K.M., Smith H.P., Warner E.D., Seegers W.H.. 1939; Heparin and blood clotting. Science 90: 539.
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    • 20 Brinkhous K.M.. 1940; Plasma prothrombin: vitamin K. Medicine 19: 329.
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    • 21 Brinkhous K.M., Warner E.D.. 1940; Effect of vitamin K on hypoprot-hrombinemia of experimental liver injury. Proc. Soc. Exp. Biol. Med. 44: 609.
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    • 22 Brinkhous K.M., Warner E.D.. 1941; Muscular dystrophy in biliary fistula dogs: possible relationship to vitamin E-deficiency. Am. J. Pathol. 17: 81.
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    • 23 Brinkhous K.M., Walker S.A.. 1941; Prothrombin and fibrinogen in lymph. Am. J. Physiol. 132: 666.
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    • 24 Seegers W.H., Warner E.D., Brinkhous K.M., Smith H.P.. 1942; Heparin and the antithrombic activity of plasma. Science 96: 300.
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    • 25 Brinkhous K.M.. 1947; Clotting defect in hemophilia: deficiency in a plasma factor required for platelet utilization. Proc. Soc. Exp. Biol. Med. 66: 117.
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    • 26 Graham J.B., Buckwalter J.A., Hartley L.J., Brinkhous K.M.. 1949; Canine hemophilia: observations on the course, the clotting anomaly and the effect of blood transfusions. J. Exp. Med. 90: 97.
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    • 27 Buckwalter J.A., Blythe W.B., Brinkhous K.M.. 1949; Effect of blood platelets on prothrombin utilization of dog and human plasmas. Am. J Physiol. 159: 316.
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    • 28 Brinkhous K.M., Graham J.B.. 1950; Hemophilia in the female dog. Science 111: 723.
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    • 29 Langdell R.D., Graham J.B., Brinkhous K.M.. 1950; Prothrombin utilization during clotting: comparison of results with the two-stage and one-stage methods. Proc. Soc. Exp. Biol. Med. 74: 424.
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    • 30 Graham J.B., Penick G.D., Brinkhous K.M.. 1951; utilization of antihemophilic factor during clotting of canine blood and plasma. Am. J. Physiol. 164: 710.
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    • 31 Graham J.B., Collins Jr. D.L., Godwin I.D., Brinkhous K.M.. 1951; Assayof plasmaantihemophilic activityinnormal,heterozygous (hemophilia) and prothrombinopenic dogs. Proc. Soc. Exp. Biol. Med. 77: 294.
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    • 32 Penick G.D., Cronkite E.P., Godwin I.D., Brinkhous K.M.. 1951; Plasma antihemophilic activity following total body irradiation. Proc. Soc. Exp. Biol. Med. 78: 732.
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    • 33 Graham J.B., McLendon W.W., Brinkhous K.M.. 1953; Mild hemophilia: an allelic form of the disease. Am. J. Med. Sci. 22: 46.
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    • 34 Langdell R.D., Wagner R.H., Brinkhous K.M.. 1953; Effect of antihemophilic factor on one-stage clotting tests: a presumptive test for hemophilia and a simple one-stage antihemophilic factor assay procedure. J. Lab. Clin. Med. 41: 637.
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    • 35 Graham J.B., Brinkhous K.M.. 1953; Christmas disease. Brit. Med. J. 2: 97.
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    • 36 Penick G.D., Taylor C.B., Huffines W.D., Roberts H.R., Wilson S.G., Brinkhous K.M.. 1953 Comparative study of responses of normal and hemophilic dogs to local cold injury. U.S.A.F. School of Aviation Medicine, Project No. 21-1202-0001, Report No. 6.
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    • 37 Brinkhous K.M., Langdell R.D., Penick G.D., Graham J.B., Wagner R. H.. 1954; Newer approaches to the study of hemophilia and hemophilioid states. J.A.M.A. 154: 481.
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    • 38 Brinkhous K.M., Graham J.B.. 1954; Hemophilia and the hemophilioid states. Blood 9: 254.
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    • 39 Brinkhous K.M.. 1954; Hemophilia. Bull. New York Acad. Med. 3: 325.
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    • 40 Brinkhous K.M.. 1954; Plasma antihemophilic factor, biological and clinical aspects. Sang 25: 738.
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    • 41 Graham J.B., Langdell R.D., Morrison Jr. F.C., Brinkhous K.M.. 1954; Serum accelerator factors and antihemophilic factor (AHF) in early phases of clotting. Proc. Soc. Exp. Biol. Med. 87: 45.
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    • 42 Langdell R.D., Wagner R.H., Brinkhous K.M.. 1955; Antihemophilic factor (AHF) levels following transfusions of blood, plasma, and plasma-fractions. Proc. Soc. Exp. Biol. Med. 88: 212.
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    • 43 Wagner R.H., Brannan Jr. W.M., Brinkhous K.M.. 1955; Antiac-celerator (anticonvertin) activity of canine plasma and serum. Proc. Soc. Exp. Biol. Med. 89: 266.
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    • 44 Brinkhous K. M., Penick G. D., Langdell R. D., Wagner R. H., Graham L.B.. 1956; Physiologic basis of transfusion therapy in hemophilia. Arch. Pathol. 61: 6.
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    • 45 Penick G.D., Brinkhous K.M.. 1956; Relative stability of plasma antihemophilic factor (AHF) under different conditions of storage. Am J. Med. Sci. 232: 434.
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    • 46 Wagner R.H., Langdell R.D., Richardson B.A., Farreel R.A., Brinkhous K.M.. 1957; Antihemophilic factor (AHF): plasma levels after administration of AHF preparations to hemophilic dogs. Proc. Soc. Exp. Biol. Med. 96: 152.
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    • 47 Wagner R. H., Richardson B. A., Brinkhous K.M.. 1957; A study of the separation of fibrinogen and antihemophilic tactor (AHF) in canine, porcine, and human plasmas. Thromb. Diath. Haemorrh. 1: 1.
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    • 48 Penick G.D., Roberts H.R., Webster W.P., Brinkhous K.M.. 1958; Hemorrhagic states secondary to intravascular clotting. Arch. Pathol 66: 708.
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    • 49 Brinkhous K.M., LeRoy E.G., Cornell W.P., Brown R.C., Hazlehurst J.L., Vennart G. P.. 1958; Macroscopic studies of platelet agglutination: nature of thrombocyte agglutinating activity of plasma. Proc. Soc. Exp. Biol. Med. 98: 379.
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    • 50 Brinkhous K.M.. 1958; Physiopathology of hemophilia. Acta Haematol 20: 125.
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    • 51 Penick G.D., Averette Jr. H.E., Peters R.M., Brinkhous K.M.. 1958; The hemorrhagic syndrome complicating extracorporeal shunting of blood: an experimental study of its pathogenesis. Thromb. Diath. Haemorrh. 2: 218.
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    • 52 Mason R.G., LeRoy E.C., Brinkhous K.M.. 1959; Cation specificity of thrombocyte agglutinating activity (TAg) of canine plasma. Proc. Soc. Exp. Biol. Med. 102: 253.
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    • 53 LeRoy E.G., Mason R.G., Brinkhous K.M.. 1960; Species difference in platelet agglutination in man and in the dog, swine and rabbit. Am. J. Physiol. 199: 183.
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    • 54 Rodman N.F., Brinkhous K.M.. 1960; Effect of surface activated clot promoting material on the assay of antihemophilic factor (AHF). Thromb. Diath. Haemorrh. Suppl. 4: 142.
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    • 55 Shermer R.W., Mason R.G., Wagner R.H., Brinkhous K.M.. 1961; Studies on thrombin-induced platelet agglutination. J. Exp. Med. 114: 905.
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    • 56 Nye S.W., Graham J.B., Brinkhous K.M.. 1962; The partial thromboplastin time as a screening test for the detection of latent bleeders. Am. J. Med. Sci. 243: 279.
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    • 57 Rodman N.F., Mason R.G., McDevitt N.B., Brinkhous K.M.. 1962; Morphologic alterations of human blood platelets during early phases of clotting: electron microscopic observations of thin sections. Am. J. Pathol. 40: 271.
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    • 58 Mason R.G., Hocutt E.J., Wagner R.H., Brinkhous K.M.. 1962; Evolution and decay of platelet agglutinating activity in normal and pathological human plasmas. J. Lab, Clin. Med. 59: 645.
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    • 59 Brown R.C., Swanton M.C., Brinkhous K.M.. 1963; Canine hemophilia and male pseudohermaphroditism. Lab. Invest. 12: 961.
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    • 60 Rodman N.G., Mason R.G., Brinkhous K.M.. 1963; Some pathogenetic mechanisms of white thrombus formation : agglutination and self-destruction of the platelet. Fed. Proc. 22: 1356.
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    • 61 Wagner R.H., McLester W.D., Smith M., Brinkhous K.M.. 1964; Purification of antihemophilic factor (Factor VIII) by amino acid precipitation. Thromb. Diath. Haemorrh. 11: 64.
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    • 62 Brinkhous K.M.. 1964; Hemophilia - pathophysiologic studies and the evolution of transfusion therapy. Am. J. Clin. Pathol. 41: 342.
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    • 63 Roberts H.R., Penick G.D., Webster W.P., Brinkhous K.M.. 1964; The prevention of hemorrhage with anticoagulants - an exploratory study of a paradox. Ann. N. Y. Acad. Sci. 115: 67.
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    • 64 Roberts H.R., Penick G.D., Brinkhous K.M.. 1964; Intensive plasma therapy in the hemophilias. J.A.M.A. 190: 546.
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    • 65 Parks B.J., Brinkhous K.M., Harris P. F., Penick G.D.. 1964; Laboratory detection of female carriers of canine hemophilia. Thromb. Diath. Haemorrh. 12: 368.
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    • 66 Brinkhous K.M., Rodman N.F., Mason R.G.. 1964; Sequential ultrastructural changes in platelets during aggregation, rhexis, and lysis. Thromb. Diath. Haemorrh. Suppl. 13: 313.
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    • 67 Brinkhous K.M., Read M.S., Mason R.G.. 1965; Plasma thrombocyte-agglutinating activity and fibrinogen. Synergism with adenosine diphosphate. Lab. Invest. 14: 335.
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    • 68 Robinson Jr. C.W., Kress S.C., Wagner R.H., Brinkhous K.M.. 1965; Platelet agglutination and deagglutination with a sulphydryl inhibitor, methyl mercuric nitrate : relationships to platelet ATPase. Exp. Molec. Pathol. 4: 457.
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    • 69 Webster W. P., Roberts H.R., Theein G.M., Wagner R.H., Brinkhous K.M.. 1965; Clinical use of a new glycine-precipitated antihemophilic fraction. Am. J. Med. Sci. 250: 643.
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    • 70 Rodman N.F., Mason R.G., Painter J.C., Brinkhous K.M.. 1966; Fibrinogen - its role in platelet aggluniation and agglutinate stability. A study of congenital afibrinogenemia. Lab. Invest. 15: 641.
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    • 71 Hurt J.P., Wagner R.H., Brinkhous K.M.. 1966; Human antihemophilic tactor (AHF) purification. A comparison of two procedures. Thromb. Diath. Haemorrh. 75: 327.
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    • 72 Brinkhous K.M.. 1966; The detection of hemophilic carriers. Bibl. Haematol. 26: 103.
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    • 73 Webster W.P., Penkk G.D., Peacock F. F., Brinkhous K.M.. 1967; Allotransplantation of spleen in hemophilia. N. C. Med. J. 28: 505.
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    • 74 Brinkhous K.M., Mason R.G., Rodman N.F.. 1967; Fibrinogen and platelet agglutination. Thromb. Diath. Haemorrh. Suppl. 26: 79.
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    • 75 Brown R.C., Cole K.W., Cornell C.M., Brinkhous K.M.. 1968; Hemophilialike disease of swine: cytogenetic studies. Am. J. Vet. Res. 29: 1491.
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    • 76 Brinkhous K.M., Shanbrom E., Roberts H.R., Webster W. P., Fekete L., Wagner R.H.. 1968; A new high-potency glycine-precipitated antihemophilic factor (AHF) concentrate. J.A.M.A. 205: 613.
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    • 77 Brinkhous K.M., Wagner R.H., Roberts H.R., Webster W.P.. 1968; Use of aliphatic amino acid precipitated antihemophilic factor in therapy of hemophilia. Bibl. Haematol. 29 pt. 4 1104.
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    • 78 Scarborough D.E., Mason R.G., Dalldorf F.G., Brinkhous K.M.. 1969; Morphologic manifestations of blood-solid interfacial reactions. A scanning and transmission electron microscopy study. Lab. Invest. 20: 164.
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    • 79 Brinkhous K.M., Scarborough D.E.. 1969; Some mechanisms of thrombus formation and hemorrhage following trauma. J. Trauma 9: 684.
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    • 80 Brinkhous K.M., Read M.S., Rodman N.F.. 1969; Need of fibrinogen for thrombin-induced aggregation of porcine platelets. J. Lab. Clin. Med. 73: 1000.
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    • 81 Wagner R. H., Roberts H. R., Webster W. P., Shanbrom E., Brinkhous K.M.. 1969; Glycine-precipitated antihemophilic factor concentrates and their clinical use. Thromb. Diath. Haemorrh. Suppl. 35: 41.
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    • 82 Mason R.G., Scarborough D.E., Saba S.R., Brinkhous K.M., Ikenberry L.E., Kearney J. J., Clark H.G.. 1969; Thrombogenicity of some biomedical materials: platelet-interface reactions. J. Biomed. Mater. Res. 3: 615.
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    • 83 Mason R.G., Read M.S., Brinkhous K.M.. 1971; Effect of fibrinogen concentration on platelet adhesion to glass. Proc. Soc. Exp. Biol. Med. 137: 680.
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    • 84 Rodman N.F., Mason R.G., Brinkhous K.M.. 1971; Effect of a new antiaggregating chemical on the structure and function of the human platelet. Am. J. Pathol. 65: 103.
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    • 85 Brinkhous K.M., Carney C.N., Shermer R.W.. 1971; Use of high-potency antihemophilic concentrates in prophylaxis. Thromb. Diath. Haemorrh. Suppl. 43: 139.
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    • 86 Brinkhous K.M.. 1971; Current status of plasma fraction therapy in hemophilia A. Bibl. Haematol. 38 pt. 1 784.
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    • 87 Brinkhous K.M., Weiss A.E.. 1972; International Forum : Can hemophilic patients be adequately maintained with cryoprecipitates? Or is it desirable or even necessary to manufacture and administer highly concentrated AHF products?. Vox Sang. 22: 556.
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    • 88 Wysocki G.P., Brinkhous K.M.. 1972; Scanning electron microscopy of synovial membranes. Arch. Pathol. 98: 172.
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    • 89 Lundblad R.L., Webster W.P., Brinkhous K.M.. 1972; The effect of dextrose on chromatography of antihemophilic factor (factor VIII). Thromb. Res. 7: 197.
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    • 90 Brinkhous K.M., Davis P.D., Graham J.B., Dodds W.J.. 1973; Expression of linkage of genes for X-linked hemophilia A and B in the dog. Blood 41: 577.
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    • 91 Griggs T.R., Cooper H.A., Webster W.P., Wagner R.H., Brinkhous K.M.. 1973; Plasma aggregating factor (bovine) for human platelets: a marker for study of antihemophilic and von Willebrand factors. Proc. Nat. Acad. Sci. USA 70: 2814.
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    • 92 Griggs T.R., Webster W.P., Cooper H.A., Wagner R.H., Brinkhous K.M.. 1974; von Willebrand factor: gene dosage relationships and transfusion response in bleeder swine - a new bioassay. Proc. Nat. Acad. Sci. USA 71: 2087.
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    • 93 Sarje K.E., Stratton R.D., Wagner R.H., Brinkhous K.M.. 1974; Nature of von Willebrand factor: a new assay and a specific inhibitor. Proc. Nat. Acad. Sci. USA 77: 2937.
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    • 94 Nopanitaya W., Gambiel T.G., Brinkhous K.M.. 1974; Fresh water drowning. Pulmonary ultrastructure and systemic fibrinolysis. Arch. Pathol. 98: 361.
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    • 95 Allain J.P., Cooper H.A., Wagner R.H., Brinkhous K.M.. 1975; Platelets fixed with paraformaldehyde: a new reagent for assay of von Willebrand factor and platelet aggregating factor. J. Lab. Clin. Med. 85: 318.
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    • 96 Brinkhous K.M., Graham J.E., Cooper H.A., Allain J.P., Wagner R. H.. 1975; Assay of von Willebrand factor in von Willebrand’s disease and hemophilia: use of a macroscopic platelet aggregation test. Thromb. Res. 6: 267.
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    • 97 Brinkhous K.M.. 1975; Hemophilia and von Willebrand’s disease. Some biological determinants. Am. J. Clin. Pathol. 63: 609.
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    • 98 Stratton R.D., Wagner R.H., Webster W.P., Brinkhous K.M.. 1975; Antibody nature of circulating inhibitor of plasma von Willebrand factor. Proc. Nat. Acad. Sci. USA 72: 4167.
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    • 99 Weiss A.E., Webster W.P., Strike L.E., Brinkhous K.M.. 1976; Survival of transfused factor VIII in hemophilic patients treated with epsilon aminocaproic acid. Transfusion 76: 209.
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    • 100 Webster W.P., Mandel S.R., Strike L.E., Penick G.D., Griggs T.R., Brinkhous K.M.. 1976; Factor VIII synthesis : hepatic and renal allografts in swine with von Willebrand’s disease. Am. J. Physiol. 230: 1342.
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    • 101 Brinkhous K.M., Gulp H.R.. 1976; Quantitation of von Willebrand factor and an antibody inhibitor. Thromb. Res. 8 Suppl II 124.
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    • 102 Blatt P.M., Brinkhous K.M., Gulp H.R., Krauss J.S., Roberts H.R.. 1976; AHF concentrate therapy in von Willebrand’s disease: dissociation of bleeding-time factor and ristocetin-cofactor activities. J.A.M.A. 236: 2770.
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    • 103 Griggs T.R., Potter J., McClanahan S.B., Webster W.P., Brinkhous K.M.. 1977; Macromolecular factor VIII complex: functional and structural heterogeneity observed in von Willebrand swine with transfusion. Proc. Nat. Acad. Sci. USA 74: 759.
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    • 104 Brinkhous K.M., Thomas B.D., Ibrahim S.A., Read M.S.. 1977; Plasma levels of platelet aggregating factor/von Willebrand factor in various species. Thromb. Res. 77: 345.
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    • 105 Geratz J.D., Tidwell R.R., Brinkhous K.M., Mohammad S.F., Dann O., Loewe H.. 1978; Specific inhibition of platelet agglutination and aggregation by aromatic amidino compounds. Thromb. Haemost. 39: 411.
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    • 106 Read M.S., Shermer R.W., Brinkhous K.M.. 1978; Venom coaggluti-nin: An activator of platelet aggregation dependent on von Willebrand factor. Proc. Nat. Acad. Sci. USA 75: 4514.
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    • 107 Brinkhous K.M., Read M.S.. 1978; Preservation of platelet receptors for platelet aggregating factor/von Willebrand factor by air drying, freezing, or lyophilization : New stable platelet preparations for von Willebrand factor assays. Thromb. Res. 13: 591.
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    • B. Review Articles

    • 1 Brinkhous K.M., Langdell R.D., Wagner R.H.. 1958; Hemostatic disorders : hemophilia and the hemophilioid diseases. Ann. Rev. Med. 9: 159.
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    • 2 Brinkhous K. M.. 1959; Blood clotting: the plasma procoagulants. Ann. Rev. Physiol. 27: 271.
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    • 3 Brinkhous K.M., Wagner R.H.. 1959. Antihemophilic factor (AHF): some aspects of its biochemistry. Proc. of the IV th Congress of Biochemistry. Vienna, 1958, Blood Clotting Factors, Vol. 10. New York: Pergamon Press; 1.
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    • 4 Brinkhous K.M., Roberts H.R.. 1961; Thrombolysis and thrombolytic agents: a brief review. J.A.M.A., 775: 284.
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    • 5 Brinkhous K.M., Brannan W. M.. 1961. Anticoagulants. Cardiology, Vol V. A.A. Luisada Ed. New York: McGraw-Hill; 192.
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    • 6 Brinkhous K.M.. 1965; The development of our knowledge of hemophilia A and B. Hereditary Coagulation Disorders. Fibrinolysis. Scand. J. Haematol. Series Haematologica 7: 1.
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    • 7 Brinkhous K.M.. 1965. Current concepts of hemophilia. Proceedings, Institutes on Hemophilia. The National Hemophilia Foundation; Columbia University and Tulane University, H. Rusalem, Ed. New York: The National Hemophilia Foundation; 7.
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    • 8 Brinkhous K. M.. 1975. A short history of hemophilia, with some comments on the word “hemophilia”. Handbook of Hemophilia. K.M. Brinkhous and H.C. Hemker, Eds. Amsterdam: Excerpta Medica; 3.
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    • 9 Cooper H.A., Mason R.G., Brinkhous K.M.. 1976; The platelet: membrane and surface reactions. Ann. Rev. Physiol. 38: 501.
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    • C. Chapters and Articles in Books and Monographs

    • 1 Brinkhous K.M.. 1948. Initiation and acceleration factors in thrombosis. Blood Clotting and Allied Problems, Transactions of the First Conference. New York: Josiah Macy Jr., Foundation; 39.
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    • 2 Brinkhous K.M., Langdell R.D., Graham J.B.. 1950. The problem of prothrombin determinations in serum. Blood Clotting and Allied Problems, Transact. Third Conf. New York: Josiah Macy Jr. Foundation; 208.
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    • 3 Brinkhous K.M.. 1951. Canine hemophilia: studies on the inheritance of the disease and the clotting defect. Proc. 3rd Congress Internat. Soc. Hematol. New York: Grune and Stratton; 439.
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    • 4 Brinkhous K.M., Graham J.B., Penick G.D., Langdell R.D.. 1951. Studies on canine hemophilia. Blood Clotting and Allied Problems, Transactions of the Fourth Conference. New York: Josiah Macy Jr. Foundation; 51.
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    • 5 Penick G.D., Brinkhous K.M.. 1953. The purpuric states. Current Therapy 1953. H.F. Conn Ed. Philadelphia: Saunders; 238.
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    • 6 Penick G.D., Brinkhous K.M.. 1954. The purpuric states. Current Therapy 1954. H.F. Conn Ed. Philadelphia: Saunders; 267.
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    • 7 Brinkhous K.M., Penick G.D.. 1955. Some systemic alteration in clotting factors following local tissue injury. Thrombosis and Embolism, First Internat. Conf. Basel: Benno Schwabe; 428.
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    • 8 Langdell R.D., Wagner R. H., Brinkhous K. M.. 1955. Estimation of antihemophilic activity by the partial thromboplastin time technic. The Coagulation of Blood. L.M. Tocantins Ed. New York: Grune and Stratton; 72.
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    • 9 Graham J. B., Penick G.D., Brinkhous K.M.. 1955. Estimation of antihemophilic activity by the prothrombin utilization technic. The Coagulation of Blood. L.M. Tocantins Ed. New York: Grune and Stratton; 77.
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    • 10 Wagner R.H., Graham J.B., Penick G.D., Brinkhous K.M.. 1955. Estimation of prothrombin by the two-stage method. The Coagulation of Blood. L.M. Tocantins Ed. New York: Grune and Stratton; 105.
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    • 11 Graham L.B., Langdell R.D., Brinkhous K.M.. 1955. Estimation of the rate of prothrombin utilization. The Coagulation of Blood. L.M. Tocantins Ed. New York: Grune and Stratton; 117.
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    • 12 Brinkhous K.M.. 1958. Antihemophilic factor (AHF) of plasma and plasma fractions. Proc. 6th Congress of International Society of Hematology. New York: Grune and Stratton; 463.
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    • 13 Langdell R.D., Brinkhous K.M.. 1960. The hemorrhagic disorders. Current Therapy 1960. H.F. Conn Ed. Philadelphia: Saunders; 190.
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    • 14 Langdell R.D., Brinkhous K.M.. 1961. The hemorrhagic disorders. Current Therapy 1961. H.F. Conn Ed. Philadelphia: Saunders; 189.
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    • 15 Mason R.G., Le Roy E.C., Brinkhous K.M.. 1961. Natural thrombocyte agglutinating system: thrombocyte agglutinating factors (TAg and Tag’) in plasma. Henry Ford Hospital International Symposium, Blood Platelets, 1960. Boston: Little, Brown; 111.
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    • 16 Brinkhous K.M., Geratz J.D.. 1961. “Paradoxical” thrombosis and hemorrhage (Penick’s syndrome). Some intermediary sequences in its pathogenesis. International Symposium : Anticoagulants and Fibrinolysis. R.L. MacMillan and J.F. Mustard Eds. Toronto: MacMillan; 28.
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    • 17 Brinkhous K.M.. 1963. Present concepts of hemophilia. Five Lectures on Hematology. IX Congress on the International Society of Hematology, Mexico City, Sept. 1962. Mexico City, Universidad Nacional Autónoma de Mexico 93.
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    • 18 Wagner R.H., Graham J.B., Penick G.D., Brinkhous K.M.. 1964. Estimation of prothrombin by the two-stage method. Blood Coagulation, Hemorrhage, and Thrombosis. L.M. Tocantins and L.A. Kazal Eds. New York: Grune and Stratton; 159.
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    • 19 Langdell R.D., Wagner R.H., Brinkhous K.M.. 1964. Determination of the partial thromboplastin time (PTT). Blood Coagulation, Hemorrhage and Thrombosis. L.M. Tocantins and L.A. Kazal Eds. New York: Grune and Stratton; 103.
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    • 20 Langdell R.D., Webster W.P., Brinkhous K.M.. 1964. Estimation of intravascular utilization of coagulation factors. Blood Coagulation, Hemorrhage and Thrombosis. L.M. Tocantins and L.A. Kazal Eds. New York: Grune and Stratton; 504.
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    • 21 Graham J.B., Langdell R.D., Brinkhous K.M.. 1964. Estimation of the rate of prothrombin utilization. Blood Coagulation, Hemorrhage and Thrombosis. L.M. Tocantins and L.A. Kazal Eds. New York: Grune and Stratton; 165.
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    • 22 Brinkhous K.M., Wagner R.H., Mason R.G.. 1964. Estimation of platelet agglutinating activity by a semiquantitative, macroscopic technic. Blood Coagulation, Hemorrhage and Thrombosis. L.M. Tocantins and L.A. Kazal Eds. New York: Grune and Stratton; 65.
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    • 23 Langdell R.D., Wagner R.H., Brinkhous K.M.. 1964. Estimation of antihemophilic activity bythe partial thromboplastin time technic. Blood Coagulation, Hemorrhage and Thrombosis. L.M. Tocantins and L.A. Kazal Eds. New York: Grune and Stratton; 107.
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    • 24 Graham J.B., Penick G.D., Brinkhous K.M.. 1964. Estimation of antihemophilic activity by the prothrombin utilization technic. Blood Coagulation, Hemorrhage and Thrombosis. L.M. Tocantins and L.A. Kazal Eds. New York: Grune and Stratton; 112.
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    • 25 Rodman N.F., Mason R.G., Brinkhous K.M.. 1965. Ultrastructural reflections of biochemical reactions in white thrombus formation : agglutination, rhexis, and lysis of the blood platelet. Pulmonary Embolic Disease. A.A. Sasahara Ed. New York: Grune and Stratton; 32.
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    • 26 Roberts H.R., Penick G.D., Brinkhous K.M.. 1966. The hemophilias. Surgical Bleeding. Handbook for Medicine, Surgery and Specialties. A.W. Ulin and S.S. Gollub Eds. New York: McGraw-Hill; 93.
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    • 27 Brinkhous K.M., Swanton M.C., Webster W.P., Roberts H.R.. 1966. Hemophilic arthropathy : Transfusion therapy in its amelioration - canine and human studies. Proc. Symp. on Haemophilia. Sydney, Australia: 18.
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    • 28 Brinkhous K.M., Mason R.G., Rodman N.F.. 1967. Platelet agglutinating factors in an afibrinogenemic boy. Proc. 10th Cong. Eur op. Soc. Haematol. pt. II. Basel: Karger; 1106.
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    • 29 Brinkhous K. M., Mason R. G., Read M. S., Shermer R. W.. 1968. Studies of agglutinability of “aged” human platelets. Metabolism and Membrane Permeability of Erythrocytes and Thrombocytes. Deutsch E., Gerlach E., Moser K.. Eds. Stuttgart: Georg Thieme; 302.
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    • 30 Brinkhous K.M.. 1968. Some mechanisms of thrombus formation and hemorrhage following trauma. Accident Pathology. Brinkhous K.M.. Ed. National Highway Bureau: U.S. Government Printing Office; 126.
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    • 31 Brinkhous K.M.. 1970. Development and use of high-potency glycine-pre-cipitated antihemophilic factor (Factor VIII) fractions. Hemophilia and New Hemorrhagic States. K.M. Brinkhous Ed. Chapel Hill: University of North Carolina Press; 57.
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    • 32 Brinkhous K.M., Shermer R.W.. 1971. The platelet in perspective. The Platelet. K.M. Brinkhous R.W. Shermer Eds. Baltimore: Williams and Wilkins; 387.
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    • 33 Brinkhous K.M.. 1971. The role of blood platelets in thrombosis. Symposium on Hemostasis and Thrombosis. H.J. Weiss Ed. Bloomfield, N.J.: Schering Diagnostics; 46.
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    • 34 Brinkhous K.M., Mason R.G.. 1972; Fibrinogen: requirement for platelet aggregation and adhesion. Acta Univ. Carol. Med. Monographia LIII-LIV: 9.
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    • 35 Mason R.G., Shermer R.W., Zucker W.H., Brinkhous K.M.. 1973. Platelets and plasma protein reactions with foreign surfaces. Erythrocytes, Thrombocytes, Leukocytes. Recent Advances in Membrane and Metabolic Research. E. Gerlach K. Moser E. Deutsch and W. Wilmanns Eds. Stuttgart: Georg Thieme; 263.
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    • 36 Weiss A.E., Brinkhous K.M.. 1973. Pathogenesis and incidence of the hemophilias. Comprehensive Management of Musculoskeletal Disorders in Hemophilia. N.C. McCollough Ed. Washington: National Academy of Sciences; 3.
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    • 37 Weiss A.E., Brinkhous K.M.. 1973. Hemarthroses and hemarthropathy in hemophilia A and B : pathologic alterations and their amelioration by prompt transfusion therapy. Comprehensive Management of Musculoskeletal Disorders in Hemophilia. N.C. McCollough Ed. Washington: National Academy of Sciences; 23.
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    • 38 Cederbaum A. I., Brinkhous K.M.. 1973. Therapy of hemophilia A and B with plasma and plasma fractions. Comprehensive Management of Musculoskeletal Disorders in Hemophilia. N.C. McCollough Ed. Washington: National Academy of Sciences; 52.
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    • 39 Hilgartner M.W., Hoag S., Brinkhous K.M., Neiman K.M.W., Lazerson J.. 1973. Basic Research. Comprehensive Management of Musculoskeletal Disorders in Hemophilia. N.C. McCollough Ed. Washington: National Academy of Sciences; 173.
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    • 40 Mason R.G., Brinkhous K.M.. 1973. Platelet thromboembolism: some pathogenetic mechanisms. Pulmonary Thromboembolism. K.M. Moser M. Stein Eds. Chicago: Year Book Medical Publishers; 21.
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    • 41 Mason R.G., Sarji K.E., Brinkhous K.M.. 1974. Antithrombotic agents: their effects on platelets and methods for their evaluation. Principles and Techniques of Human Research and Therapeutics Vol. V. Cardiovascular Drugs. F.G. McMahon Ed. E.D. Fröhlich F.H. Gross R.F. Palmer A.J. Seaman Assoc. Eds. Mount Kisco, N.Y.: Futura; 183.
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    • 42 Dodds W.J., Webster W.P., Brinkhous K.M., Owen C.A., Bowie E.J.W.. 1975. Porcine and canine von Willebrand’s disease. Handbook of Hemophilia. K.M. Brinkhous and H.C. Hemker Eds. Amsterdam: Excerpta Medica; 141.
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    • 43 Brinkhous K.M., Griggs T.R., Sarji K.E., Allain J.P., Cooper H.A., Wagner R.H., Webster W.P.. 1975. Approaches to bioassay for von Willebrand factor utilizing platelet aggregating tests. Platelets. O.N. Ulutin Ed. Amsterdam: Excerpta Medica; 414.
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    • 44 Binkhous K.M.. 1977. Pathogenesis of thrombosis - some mechanisms. Topics in Hematology. S. Seno F. Takaku S. Irino Eds. Amsterdam: Excerpta Medica; 59.
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    • D. Books and Monographs

    • 1 K.M. Brinkhous Ed. 1957. Hemophilia and Hemophilioid Diseases. Chapel Hill: University of North Carolina Press; 275 pp.
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    • 2 K.M. Brinkhous P. De Nicola Eds. 1959. Hemophilia and Other Hemorrhagic States. Chapel Hill: University of North Carolina Press; 266 pp.
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    • 3 K.M. Brinkhous Ed. 1964. The Hemophilias. Chapel Hill: University of North Carolina Press; 412 pp.
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    • 4 Platelets: Their Role in Hemostasis and Thrombosis. Thrombos. Diathes. Haemorrh. Suppl.. 26. 1967 K.M. Brinkhous H.R. Roberts S. Hinnom Eds.
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    • 5 Brinkhous K.M.. Ed. 1968. Accident Pathology. Proceedings of an International Conference. U.S. Government Printing Office; 249 pp.
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    • 6 Sherry S., Brinkhous K.M., Genton E., Stengle J.M.. Eds. 1969. Thrombosis. Washington: National Academy of Sciences; 762 pp.
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    • 7 Plasma Fractions for the Treatment of Hemophilia. Anticoagulant Therapy: Standardization of Tests. Thrombos. Diathes. Haemorrh.. Suppl. 35. 1969 K.M. Brinkhous H.R. Roberts A.J. Johnson S. Hinnom Eds.
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    • 8 K.M. Brinkhous Ed. 1970. Hemophilia and New Hemorrhagic States. Chapel Hill: University of North Carolina Press; 296 pp.
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    • 9 Fibrinogen : Structural, Metabolic and Pathophysiologic Aspects. Thrombos. Diathes. Haemorrh. Suppl.. 39. 1970 K.M. Brinkhous H.R. Roberts S. Hinnom T.H. Kiesselbach Eds.
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    • 10 Vascular Factors and Thrombosis. Thrombos. Diathes. Haemorrh. Suppl.. 40. 1970 K.M. Brinkhous N.F. Rodman S. Hinnom Eds.
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    • 11 Immunological Mechanisms in Blood Coagulation, Thrombosis and Hemostasis. New Developments in Antithrombotic Therapy. Thrombos. Diathes. Haemorrh.. Suppl. 45. 1971 F. Duckert K.M. Brinkhous S. Hinnom Eds.
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    • 12 Thrombosis: Risk Factors and Diagnostic Approaches. Thrombos. Diathes. Haemorrh.. Suppl. 51. 1972 K.M. Brinkhous S. Hinnom Eds.
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    • 13 Brinkhous K.M., Johnson J.H.. 1972. Thrombus. A Syllabus for Medical Students. Kalamazoo: The Upjohn Co.; 32 pp.
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    • 14 Thrombosis : Mechanisms and Control. Thrombos. Diathes. Haemorrh.. Suppl. 54. 1973 K.M. Brinkhous S. Hinnom Eds.
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    • 15 Brinkhous K.M., Hemker H.C.. Eds. 1975. The Handbook of Hemophilia. Amsterdam: Excerpta Medica; 927 pp.
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