CC BY-NC-ND 4.0 · Laryngorhinootologie 2019; 98(S 02): S148-S149
DOI: 10.1055/s-0039-1686479
Abstracts
Otology

Development of a novel middle-ear electrode for tinnitus suppression – proof of concept

U Reich
1   Klinik für HNO-Heilkunde der Charité Berlin, Berlin
,
A Szczepek
1   Klinik für HNO-Heilkunde der Charité Berlin, Berlin
,
F Uecker
1   Klinik für HNO-Heilkunde der Charité Berlin, Berlin
,
S Gräbel
1   Klinik für HNO-Heilkunde der Charité Berlin, Berlin
,
J Vater
1   Klinik für HNO-Heilkunde der Charité Berlin, Berlin
,
H Olze
1   Klinik für HNO-Heilkunde der Charité Berlin, Berlin
› Author Affiliations
gefördert durch das BMBF, Netzwerk INTAKT
 

Tinnitus is a phantom sound without external source. In Germany, round 10 million people are impaired by tinnitus. Intriguingly, hearing-impaired patients with cochlear implant often report reduction of their tinnitus following the implantation. Such reduction is presumably not only due to recovery of patients' hearing abilities but also due to the electrical stimulation. However, electrical stimulation therapy is not available for tinnitus patients without hearing loss.

The aim of our project is to determine the individual tinnitus suppression parameters to be used in clinical trials as well as to establish an animal model for testing the new middle ear tinnitus-suppressing electrodes.

The clinical part uses a routine clinical diagnostic step prior to cochlear implantation, namely stimulation via external ear canal. The already implanted patients can be stimulated directly via their cochlear electrode. The efficiency of stimulation (duration approximately two minutes), is determined by collecting several tinnitus parameters bevor, during, and after the stimulation. The patients react in a various ways by a temporary tinnitus suppression during and/or after the electrical stimulation.

In addition, the focus of preclinical study is on determining the shape, size and flexibility of new electrodes. For the first implantation tests, polyimide based electrode carrier are used. Guinea pig are used as an animal model to determine the performance of the tinnitus-suppressing implants.



Publication History

Publication Date:
23 April 2019 (online)

© 2019. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).

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