CC BY-NC-ND 4.0 · Laryngorhinootologie 2019; 98(S 02): S310
DOI: 10.1055/s-0039-1686358
Georg Thieme Verlag KG Stuttgart · New York

Objective assessment of vertigo causing perilymphatic fistula in cochlear implantees by cochlin-tomoprotein (CTP)

A Darwish
1  Klinikum Bielefeld, Bielefeld
H Sudhoff
1  Klinikum Bielefeld, Bielefeld
I Todt
1  Klinikum Bielefeld, Bielefeld
› Institutsangaben
Weitere Informationen


23. April 2019 (online)



A well-known and frequently reported complication after cochlear implantation is the appearance of postoperative vertigo symptoms. Perilymphatic fistula (PLF) is a known cause for hearing loss and vertigo. Cochlin-tomoprotein (CTP) is a cochlear specific protein acting as a marker for PLF. Aim of the present study was to observe, if the postoperatively new occurence of vertigo is caused by a perilymphatic fistula evidenced by CTP marker.


In a prospective analysis 12 cochlear implant patients with the postoperatively new occurence ofvertigo underwent a transtympanallyrevison/resealing surgery. In all patients middle ear fluid was captured and analysed for CTP.


In 5 out of 12 patients a positive CTP result was found indicating a PLF. Positive PLF finding did not correlate with the intraoperative visual assumption of a leak. The procedure solves in most of the cases the vertigo problem.


Our present finding demonstrates that objectively an insufficent sealing causing perilymphatic fistula occurs in cases of newly postoperative vertigo after cochlea implantation.