Laryngeal Carcinoma in Sarajevo Canton

Introduction:

Aim of the study was to estimate incidence of laryngeal carcinoma in the Canton of Sarajevo in 2017, mean age of disease onset, distribution of T stages, histological findings and treatment options.

Methods:

Retrospectively study based on data from medical records of patients treated in ENT clinic in Clinical Center University of Sarajevo, with standard statistical analysis.

Results:

Study included 66 patients, 49 males (79%) and 13 females (20.9%), mean age 63. Glottic carcinomas represent the majority of laryngeal cancers 31 (50%), followed by transglottic 17 (27.4%), supraglottic 13 (20.9%) and subglottic 1 (1.6%). Different dysplastic lesions (ranging from squamous hyperplasia to carcinoma in situ) were found in 18 (29%), and 44 (70.9%) were malignancies. The vast majority of these malignancies are squamous cell carcinomas detected in 42 cases (95.4%), a adenocarcinoma and 1 B-cell lymphoma (2.27%). At the time of first diagnosis, 6 patients (13.6%) were in stage T1, 14 (31.8%) in T2, 13 (29.5%) in T3 and 11 (25%) in T4. Surgical therapy performed in 26 patients (59%); in 13 cases of that (29.5%) were open partial laryngeal resection procedures (7 partial laryngectomy alone, and 6 with neck dissection); and also in 13 (29.5%) performed total laryngectomy, all with neck dissections. Combined surgical and oncology procedure performed in 19 cases (43.2%), and oncology procedure alone in 11 (25%).

Conclusions:

Incidence of laryngeal carcinoma in the Canton of Sarajevo in the previous year was about 9 new cases per 100.000, which ranks this area in higher incidence. It should be concerned that the majority of laryngeal cancer cases are diagnosed in an advanced stage, which significantly reduces the curability and survival rate.

Publication History

Publication Date:
23 April 2019 (online)