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DOI: 10.1055/s-0039-1686020
Large cell neuroendocrine carcinoma of the nasopharynx
Primary neuroendocrine tumors of the head and neck are a very rare entity. Poorly differentiated neuroendocrine carcinomas are highly aggressive tumors associated with a high propensity for recurrence, distant metastasis and poor survival rates.
We report on the case of a 50-year-old male patient who initially presented with mild hearing loss due to middle ear effusion. Clinical workup led to the diagnosis of a nasopharyngeal large cell neuroendocrine carcinoma. The patient was treated with combined radiochemotherapy.
Publication History
Publication Date:
23 April 2019 (online)
© 2019. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).
Georg Thieme Verlag KG
Stuttgart · New York