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Semin Hear 2019; 40(02): 087-096
DOI: 10.1055/s-0039-1684038
Review Article
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Pharmacology for the Audiologist

Tracy Offerdahl
1   Osborne College of Audiology, Salus University, Elkins Park, Pennsylvania
,
Vallabhi Mishra
2   Temple University School of Pharmacy, Philadelphia, Pennsylvania
› Author Affiliations
Further Information

Publication History

Publication Date:
26 April 2019 (online)

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Abstract

The purpose of this article is to provide a brief introduction and review regarding basic principles of pharmacology, including terminology and colloquialisms, as well as pharmacokinetic and pharmacodynamic principles of ototoxic agents. As an audiology practitioner, it is more important than ever to have a working knowledge regarding the known and proposed mechanisms of action for drugs and chemicals with known ototoxicity potential. Additionally, this article provides a discussion regarding the biochemistry behind distribution, which is a major step in determining ototoxic potential of known and potential ototoxins.

Keywords

pharmacokinetics - pharmacodynamics - ototoxicity - distribution - ADMET
 

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