Clin Colon Rectal Surg 2019; 32(04): 305-313
DOI: 10.1055/s-0039-1683923
Review Article
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Crohn's Disease and the Risk of Cancer

Evie Carchman
1   Department of Surgery, University of Wisconsin, Madison, Wisconsin
› Author Affiliations
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Publication History

Publication Date:
02 July 2019 (online)

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Abstract

Crohn's disease is associated with various intestinal and extraintestinal malignancies. This article reviews the current literature regarding Crohn's disease and subsequent risk of cancer formation. Recognition of risk factors (both modifiable and unmodifiable) is essential for prevention and appropriate screening. Future investigations into the molecular mechanisms associated with Crohn-related malignancy will provide additional insight into carcinogenesis, potential for early intervention, and identification of at-risk patients.