J Pediatr Neurol
DOI: 10.1055/s-0039-1683870
Case Report
Georg Thieme Verlag KG Stuttgart · New York

Brain Tuberculomas as BCGitis Complication Presenting with Epileptic Spasms: A Case Report

Basma Ayadi
1  Child Neurology Department, Hedi Chaker University Hospital, Sfax, Tunisia
,
Fatma Kamoun Feki
1  Child Neurology Department, Hedi Chaker University Hospital, Sfax, Tunisia
2  Child Neurology Department Search Unit “Neuropédiatrie” UR12ES16, Sfax University- Tunisia
,
Siham Ben Nsir
1  Child Neurology Department, Hedi Chaker University Hospital, Sfax, Tunisia
2  Child Neurology Department Search Unit “Neuropédiatrie” UR12ES16, Sfax University- Tunisia
,
Wafa Bouchaala
1  Child Neurology Department, Hedi Chaker University Hospital, Sfax, Tunisia
2  Child Neurology Department Search Unit “Neuropédiatrie” UR12ES16, Sfax University- Tunisia
,
Zeineb Mnif
3  Radiology Department, Hedi Chaker University Hospital, Sfax, Tunisia
,
Mounir Ben Jemaa
4  Department of Infectious Diseases, Hedi Chaker University Hospital, Sfax, Tunisia
,
Chahnez Triki
1  Child Neurology Department, Hedi Chaker University Hospital, Sfax, Tunisia
2  Child Neurology Department Search Unit “Neuropédiatrie” UR12ES16, Sfax University- Tunisia
› Author Affiliations
Further Information

Publication History

02 December 2018

11 February 2019

Publication Date:
13 March 2019 (eFirst)

Abstract

Central nervous system (CNS) BCGitis is a rare but a very severe complication of the Bacille Calmette–Guerin (BCG) vaccine. It could be a diagnostic challenge that may lead to a delay in treatment. A 5-month-old boy presented with infantile spasms, had posted natal BCG vaccination and developed brain tuberculomas as brain BCGitis. Laboratory findings were normal. He received 14 months of antitubercular regimen with good tolerance and both clinical and radiological improvement. The main difficulty in brain BCGitis is to make a diagnosis that requires histological or bacteriological examination. A good evolution without sequel could be seen if it is treated early.