J Pediatr Neurol
DOI: 10.1055/s-0039-1683440
Case Report
Georg Thieme Verlag KG Stuttgart · New York

Central Nervous System Complications due to Human Herpesvirus 6 Infection in Pediatric Age Group

C. Barrea
1  Department of Paediatrics, Centre Hospitalier Chrétien, CHC, Liège, Belgium
,
N. Demonceau
2  Department of Neuropédiatrics, Centre Hospitalier Chrétien, CHC, Liège, Belgium
,
I. Loeckx
3  Pediatric Intensive Care Unit, Centre Hospitalier Chrétien, CHC, Liège, Belgium
,
J-M Senterre
4  Master in Paediatrics, University of Liège, ULg, Belgium
,
P. Philippet
1  Department of Paediatrics, Centre Hospitalier Chrétien, CHC, Liège, Belgium
› Author Affiliations
Further Information

Publication History

11 January 2019

08 February 2019

Publication Date:
13 March 2019 (eFirst)

Abstract

Human herpesvirus 6 (HHV-6) has been demonstrated to be a neurotropic virus and has been linked to several neurological complications associated with a wide range of clinical outcomes. Here, we present data from immunocompetent children with a central neurological condition and intrathecal DNA detection of HHV-6 virus. Through these cases, physiopathology, investigations, and outcome of the disease will be described. Finally, specific treatment will be discussed.