J Pediatr Neurol
DOI: 10.1055/s-0039-1683367
Case Report
Georg Thieme Verlag KG Stuttgart · New York

Reversible Splenial Lesion Syndrome Associated with Encephalitis/Encephalopathy and Hyponatremia

Serdal Güngör
1  Department of Pediatric Neurology, Faculty of Medicine, İnönü University, Malatya, Turkey
,
Betül Kılıç
1  Department of Pediatric Neurology, Faculty of Medicine, İnönü University, Malatya, Turkey
,
Mahmut Aslan
1  Department of Pediatric Neurology, Faculty of Medicine, İnönü University, Malatya, Turkey
,
Bilge Özgör
1  Department of Pediatric Neurology, Faculty of Medicine, İnönü University, Malatya, Turkey
› Author Affiliations
Further Information

Publication History

14 November 2018

24 January 2019

Publication Date:
25 March 2019 (eFirst)

Abstract

Reversible splenial lesion syndrome (RESLES) is a rare occurrence with a broad clinical and radiological spectrum due to several conditions and diseases. Generally, clinical symptoms of RESLES include mildly altered states of consciousness, delirium, and seizures. RESLES can be shown in conjunction with central nervous system infections, especially in children. Hyponatremia is also described as a potential cause of reversible splenial lesions. Reversible signal changes on diffusion-weighted images are detected in patients for diagnosis. The prognosis is usually good but it depends on the underlying disease, neurological and imaging findings. Here we present two pediatric patients with RESLES accompanied by hyponatremia.