Endoscopy 2019; 51(04): S242
DOI: 10.1055/s-0039-1681898
ESGE Days 2019 ePosters
Friday, April 5, 2019 09:00 – 17:00: Esophagus ePosters
Georg Thieme Verlag KG Stuttgart · New York

AUGSBURGER ZENKER QUESTIONNAIRE – ACQUISITION OF SYMPTOMS AND MONITORING DURING FOLLOW-UP OF PATIENTS WITH ENDOSCOPIC TREATMENT OF SYMPTOMATIC ZENKER'S DIVERTICULUM

J Manzeneder
1   Klinikum Augsburg, Department of Internal Medicine III, Augsburg, Germany
,
C Römmele
1   Klinikum Augsburg, Department of Internal Medicine III, Augsburg, Germany
,
S Gölder
1   Klinikum Augsburg, Department of Internal Medicine III, Augsburg, Germany
,
D Freuer
2   Ludwig-Maximilians University of Munich, Chair for Epidemiology at UNIKA-T, Augsburg, Germany
,
H Messmann
1   Klinikum Augsburg, Department of Internal Medicine III, Augsburg, Germany
› Author Affiliations
Further Information

Publication History

Publication Date:
18 March 2019 (online)

Also available at
 

Aims:

The frequency and severity of symptoms of Patients with Zenker's diverticulum have been acquired by a newly developed questionnaire (Augsburger Zenker Questionnaire – AQZ). A cumulative score was generated that should help to recognize patients with symptomatic recurrence during follow-up.

Methods:

From August 2014 to July 2018 n = 97 patients with symptomatic Zenker's diverticulum were treated with flexible endoscopy. The symptoms of the patients were recorded by an eight-item questionnaire prior to treatment and 1 and 6 months post-interventional. The questionnaire asked for the Dakkak's dysphagia score, the frequency of dysphagia, odynophagia, regurgitation, vomiting, dry cough, halitosis and nocturnal awakening due to Zenker related symptoms on an ordinal scale with values from zero to four. The scores of the single symptoms were added to a total score (0 to maximum 68 points) whereas according to our clinical experience frequent and more specific symptoms were higher rated. In case of readmission with recurrence the score was raised again and compared with the score of recurrence-free patients.

Results:

The median value prior to treatment was 41.0 (32.0 – 45.8). Patients, who developed a recurrence later on showed already before intervention a tendency for higher values (44.0 vs. 36.0 of recurrence-free patients, p = 0.09). The median value one month after treatment was 5.0 (0 – 12.3) and after six months 9 (0 – 18.0). Patients with recurrence (n = 13) stated a value of 32.5 (24.8 – 45.0) before the retreatment.

In the follow-up a value of ≥26 shows a high probability for recurrence (specificity 98.7%, sensitivity 75%, PPV: 92%, NPV 95%). Patients with values less than 21 most likely had no recurrence (NPV 97%).

Conclusions:

We described the first time a specific questionnaire for patients with symptomatic Zenker's diverticulum. It records extensively the symptoms prior to treatment. It can be a helpful tool to calculate the probability of symptomatic recurrence in patients after flexible endoscopic treatment.