Endoscopy 2019; 51(04): S223-S224
DOI: 10.1055/s-0039-1681838
ESGE Days 2019 ePosters
Friday, April 5, 2019 09:00 – 17:00: Endoscopic ultrasound ePosters
Georg Thieme Verlag KG Stuttgart · New York

FEASIBILITY AND EFFICACY OF A NOVEL NEEDLE IN ENDOSCOPIC ULTRASOUND-GUIDED TISSUE SAMPLING FOR PANCREATIC SOLID LESIONS: A PROSPECTIVE RANDOMIZED COMPARATIVE STUDY

CM Cho
1   Internal Medicine, School of Medicine, Kyungpook National University, Daegu, Korea, Republic of
,
SJ Yeo
1   Internal Medicine, School of Medicine, Kyungpook National University, Daegu, Korea, Republic of
,
AN Seo
2   Pathology, School of Medicine, Kyungpook National University, Daegu, Korea, Republic of
,
HI Bae
2   Pathology, School of Medicine, Kyungpook National University, Daegu, Korea, Republic of
› Author Affiliations
Further Information

Publication History

Publication Date:
18 March 2019 (online)

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Aims:

Histologic confirmation is crucial in the evaluation of pancreatic solid lesions. Recently, variable needles with different shapes for endoscopic ultrasound-guided tissue sampling (EUS-TS) have been widely used to diagnose pancreatic lesion. However, most needles used currently are made from major companies and expensive. Therefore, it is urgent to develop an inexpensive needle with a novel concept technology. We evaluated the feasibility and efficacy of a newly developed prototype needle in EUS-TS for pancreatic solid lesions comparing the commercially available ones.

Methods:

As a prospective randomized trial, we compared between a 22-gauge needle (22G, Clear-Tip, FINEMEDIX, Daegu, Korea) with side-hole of both reversed bevel (test needle) and three commercially available 22G biopsy needles (control needle) in patients with undergoing EUS-TS of pancreatic solid lesions. First two passes of EUS-TS were accomplished in a random order between test and control needles. The procured specimens were prepared for the comparison of specimen adequacy and diagnostic accuracy to final diagnosis. Additional two passes were performed using the control needle for histologic diagnosis. Two blinded pathologists evaluated the specimens based on an already agreed diagnostic criteria for cytology and histology.

Results:

Between February and June 2018, 24 patients (median 63.5 years, 14 males) with pancreatic solid lesions were enrolled. Among them, one patient had no final diagnosis due to inadequate specimen. Technical failure occurred in one case of test needle. There was no significant difference between test and control needles in terms of specimen adequacy (91.3% vs. 95.8%) and diagnostic accuracy (72.7% vs. 82.6%) (p value = 0.456 and 0.331, respectively).

Conclusions:

The new prototype needle is feasible and efficient for EUS-TS in pancreatic solid lesions. However, further study including large volume and for other lesions is needed to validate these results.