J Pediatr Neurol
DOI: 10.1055/s-0039-1678662
Case Report
Georg Thieme Verlag KG Stuttgart · New York

The Rare Case of Anti-VGKC Limbic Encephalitis Secondary to High-Grade Glioma

DeJarra Caprii Johnson
1  University of South Alabama College of Medicine, Mobile, Alabama, United States
2  Department of Pediatrics, Children's and Women's Hospital, Mobile, Alabama, United States
,
David Edward Feldman
3  Department of Radiology, USA Health University Hospital, Mobile, Alabama, United States
,
Preethi Marri
2  Department of Pediatrics, Children's and Women's Hospital, Mobile, Alabama, United States
4  Division of Hematology-Oncology, Children's and Women's Hospital, Mobile, Alabama, United States
› Author Affiliations
Further Information

Publication History

30 August 2018

09 January 2019

Publication Date:
21 February 2019 (eFirst)

Abstract

Introduction Paraneoplastic limbic encephalitis secondary to a glial tumor is rare, and limited reports on this occurrence have been made in the pediatric population.

Case Report This case involves a 13-year-old female patient with anti-voltage gated potassium channel (anti-VGKC) limbic encephalitis secondary to a high-grade glioma (HGG) in the suprasellar region.

Discussion HHGs, associated with anti-VGKC antibodies, are a rare occurrence. This case highlights the need for the inclusion of glial neoplasms in the differential diagnosis for patients presenting with symptoms associated with paraneoplastic encephalitis.